Diabetes mellitus is one of the biggest challenges for the scientific community in the 21st
century. It is a well-recognized multifactorial health problem contributes significantly to high …

Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …

A series of novel compounds carrying 1, 2, 4-triazole scaffold was synthesized and
evaluated for their anticancer activity against a panel of cancer cell lines using MTT assay …

In this paper, thiosemicarbazide derivatives were synthesized as potential anticancer
agents. X-ray investigations for 1-(2, 4-dichlorophenoxy) acetyl-4-(2-fluorophenyl) …

A new series of isatin based thiosemicarbazide derivatives 1–15 were synthesized and
characterized by 1 H NMR, 13 C NMR and HR-EIMS. The synthetic derivatives were …

In this study, a new series of quinazolinone-1, 2, 3-triazole-acetamide hybrids 8a–m, using
by molecular hybridization of the potent α-glucosidase inhibitor pharmacophores, was …

Numerous epidemiological studies report an increased risk of developing prostate cancer in
patients with melanoma and an increased risk of developing melanoma in patients with …

A series of thiosemicarbazide derivatives was designed and synthesized by reaction of
carboxylic acid hydrazide with isothiocyanates. The molecular structures of the investigated …

The optimization and synthesis of new CK2 and CK1 inhibitors are the basis for the
development of new therapeutic strategies for the treatment of cancer and …

The aim of the studies was to evaluate the antiproliferative potential against human tumor
cell lines of newly synthetized derivatives containing 4-nitrophenyl group, as well as its …