[PDF][PDF] Transforming toxicity assessment through microphysiology, bioprinting, and computational modeling

TA Addissouky, Y Wang… - Advances in Clinical …, 2024 - researchgate.net
Background: Traditional toxicity testing emphasizes animal models with growing concerns
regarding predictive capacity, throughput and ethics. Rapid innovation surrounding human …

Recapitulation of Cellular Senescence, Inflammation, and Fibrosis in Human Kidney-Derived Tubuloids by Repeated Cisplatin Treatment

Y Nakao, Y Mori, M Mori, S Mandai, T Fujiki, H Kikuchi… - medRxiv, 2024 - medrxiv.org
In the pursuit of more accurate pathophysiological models for assessing renal drug
response, the development of kidney organoids derived from human pluripotent stem cells …