Therapeutic efficacy and promise of stem cell-derived extracellular vesicles in Alzheimer's disease and other aging-related disorders

HA Rather, S Almousa, S Craft, G Deep - Ageing Research Reviews, 2023 - Elsevier
The term extracellular vesicles (EVs) refers to a variety of heterogeneous nanovesicles
secreted by almost all cell types, primarily for intercellular communication and maintaining …

The Crosstalk between Mesenchymal Stromal/Stem Cells and Hepatocytes in Homeostasis and under Stress

IV Kholodenko, RV Kholodenko… - International Journal of …, 2023 - mdpi.com
Liver diseases, characterized by high morbidity and mortality, represent a substantial
medical problem globally. The current therapeutic approaches are mainly aimed at reducing …

Stem cell-derived extracellular vesicles as senotherapeutics

E Rudnitsky, A Braiman, M Wolfson… - Ageing Research …, 2024 - Elsevier
Cellular senescence (CS) is recognized as one of the hallmarks of aging, and an important
player in a variety of age-related pathologies. Accumulation of senescent cells can promote …

Multi-omics reveals the role of MCM2 and hnRNP K phosphorylation in mouse renal aging through genomic instability

R Yan, Y Song, D Liu, W Yu, Y Sun, C Tang… - Experimental Cell …, 2024 - Elsevier
The process of aging is characterized by structural degeneration and functional decline, as
well as diminished adaptability and resistance. The aging kidney exhibits a variety of …

Multi-omics reveals aging-related pathway in natural aging mouse liver

C Tang, Z Zhang, Y Sun, W Ding, X Yang, Y Song… - Heliyon, 2023 - cell.com
Aging is associated with gradual changes in liver structure, altered metabolites and other
physiological/pathological functions in hepatic cells. However, its characterized phenotypes …