Recent advancements in the regeneration of auditory hair cells and hearing restoration
R Mittal, D Nguyen, AP Patel, LH Debs… - Frontiers in molecular …, 2017 - frontiersin.org
Neurosensory responses of hearing and balance are mediated by receptors in specialized
neuroepithelial sensory cells. Any disruption of the biochemical and molecular pathways …
neuroepithelial sensory cells. Any disruption of the biochemical and molecular pathways …
Approaches to purification and concentration of rAAV vectors for gene therapy
L Belova, K Kochergin‐Nikitsky, A Erofeeva… - …, 2022 - Wiley Online Library
Recombinant adeno‐associated viruses (rAAVs) are promising vectors for the delivery of
various genetic constructs into eukaryotic cells. rAAVs have a number of properties that …
various genetic constructs into eukaryotic cells. rAAVs have a number of properties that …
Induced liver regeneration enhances CRISPR/Cas9-mediated gene repair in tyrosinemia type 1
QS Zhang, A Tiyaboonchai, S Nygaard… - Human Gene …, 2021 - liebertpub.com
The efficiency of gene repair by homologous recombination in the liver is enhanced by
CRISP/Cas9 incision near the mutation. In this study, we explored interventions designed to …
CRISP/Cas9 incision near the mutation. In this study, we explored interventions designed to …
Ultrafiltered recombinant AAV8 vector can be safely administered in vivo and efficiently transduces liver
MD Kleven, MM Gomes, AM Wortham, CA Enns… - Plos one, 2018 - journals.plos.org
Viral vectors are extensively purified for use in biomedical research, in order to separate
biologically active virus particles and to eliminate production related impurities that are …
biologically active virus particles and to eliminate production related impurities that are …
Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear
BC Cox, JV Brigande, BJ Walters - Hair Cell Regeneration, 2023 - Springer
Our understanding of the cellular and molecular mechanisms that govern hair cell
regeneration in non-mammalian and mammalian species is growing at a rapid pace …
regeneration in non-mammalian and mammalian species is growing at a rapid pace …
The oligodendrocyte-enriched orphan G protein-coupled receptor Gpr62 is dispensable for central nervous system myelination
Background Myelination is a highly regulated process in the vertebrate central nervous
system (CNS) whereby oligodendrocytes wrap axons with multiple layers of insulating …
system (CNS) whereby oligodendrocytes wrap axons with multiple layers of insulating …
[图书][B] Hair Cell Regeneration
ASA Press, which represents a collaboration between the Acoustical Society of America and
Springer Nature, is dedicated to encouraging the publication of important new books as well …
Springer Nature, is dedicated to encouraging the publication of important new books as well …