Targeting ferroptosis in acute kidney injury
L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …
Ferritin–from iron, through inflammation and autoimmunity, to COVID-19
While it took decades to arrive to a conclusion that ferritin is more than an indicator of iron
storage level, it took a short period of time through the COVID-19 pandemic to wonder what …
storage level, it took a short period of time through the COVID-19 pandemic to wonder what …
Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Sepsis-Induced Acute Kidney Injury by Promoting Mitophagy of Renal Tubular Epithelial Cells via the …
J Guo, R Wang, D Liu - Frontiers in endocrinology, 2021 - frontiersin.org
Sepsis is a common risk factor for acute kidney injury (AKI). Bone marrow-derived
mesenchymal stem cells (BMSCs) bear multi-directional differentiation potential. This study …
mesenchymal stem cells (BMSCs) bear multi-directional differentiation potential. This study …
Effect of Serum Ferritin on the Prognosis of Patients with Sepsis: Data from the MIMIC‐IV Database
YP Fang, HJ Zhang, Z Guo, CH Ren… - Emergency Medicine …, 2022 - Wiley Online Library
Background. The present study aimed to investigate the prognostic value of serum ferritin in
critically ill patients with sepsis by using the MIMIC‐IV database. Methods. Data were …
critically ill patients with sepsis by using the MIMIC‐IV database. Methods. Data were …
Iron as an emerging therapeutic target in critically ill patients
C Grange, F Lux, T Brichart, L David, A Couturier… - Critical Care, 2023 - Springer
The multiple roles of iron in the body have been known for decades, particularly its
involvement in iron overload diseases such as hemochromatosis. More recently, compelling …
involvement in iron overload diseases such as hemochromatosis. More recently, compelling …
The relationship between serum ferritin level and clinical outcomes in sepsis based on a large public database
L He, C Guo, Y Su, N Ding - Scientific Reports, 2023 - nature.com
This study aimed to investigate the relationship between serum ferritin level and prognosis
in sepsis. It also explored the potential prognostic value of serum ferritin for predicting …
in sepsis. It also explored the potential prognostic value of serum ferritin for predicting …
Ferritin-mediated neutrophil extracellular traps formation and cytokine storm via macrophage scavenger receptor in sepsis-associated lung injury
H Zhang, D Wu, Y Wang, Y Shi, Y Shao, F Zeng… - Cell Communication and …, 2024 - Springer
Background Sepsis is a severe systemic inflammatory disorder manifested by a
dysregulated immune response to infection and multi-organ failure. Numerous studies have …
dysregulated immune response to infection and multi-organ failure. Numerous studies have …
Sirtuin 1 deletion increases inflammation and mortality in sepsis
BACKGROUND Sepsis is a hyperinflammatory response to infection that can lead to
multiorgan failure and eventually death. Often, the onset of multiorgan failure is heralded by …
multiorgan failure and eventually death. Often, the onset of multiorgan failure is heralded by …
Protein and peptide-based renal targeted drug delivery systems
J Lu, X Xu, X Sun, Y Du - Journal of Controlled Release, 2024 - Elsevier
Renal diseases have become an increasingly concerned public health problem in the world.
Kidney-targeted drug delivery has profound transformative potential on increasing renal …
Kidney-targeted drug delivery has profound transformative potential on increasing renal …
Feasibility study and direct extraction of endogenous free metallic cations combining hemodialysis and chelating polymer
M Natuzzi, C Grange, T Gréa, T Brichart, A Aigle… - Scientific Reports, 2021 - nature.com
In this article, we report the conception and the use of dialysis-based medical device for the
extraction of metals. The medical device is obtained by addition in the dialysate of a …
extraction of metals. The medical device is obtained by addition in the dialysate of a …