Liver disease is prevalent worldwide. When it reaches the end stage, mortality rises to 50%
or more. Although liver transplantation has emerged as the most efficient treatment for end …

Ischaemic cardiovascular diseases, including peripheral and coronary artery disease,
myocardial infarction, and stroke, remain major comorbidities for individuals with type 2 …

Cellular therapies to stimulate therapeutic angiogenesis in individuals with critical limb
ischemia (CLI) remain under intense investigation. In this context, the efficacy of cell therapy …

Metabolism plays a crucial role for cell survival and function; however, recent evidence has
implicated it in regulating embryonic development. In the embryo, the inner cell mass …

The enzymes that belong to the aldehyde dehydrogenase family are expressed in a variety
of cells; yet activity of their main members characterizes stem cells, both normal and …

Multipotent/mesenchymal stromal cells (MSCs) exist within a variety of postnatal tissues;
however, global proteomic analyses comparing tissue-specific MSC are limited. Using …

Background The cutaneous wound healing process mainly comprises re-epithelialization,
fibrosis, and neovascularization. Impaired wound healing is common but tricky in plastic …

The secretome of mesenchymal stromal cells (MSCs) is enriched for biotherapeutic effectors
contained within and independent of extracellular vesicles (EVs) that may support tissue …

As caretakers of the hematopoietic system, hematopoietic stem cells assure a lifelong supply
of differentiated populations that are responsible for critical bodily functions, including …

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2
(SGLT2) inhibitors are guideline-recommended therapies for the management of type 2 …