After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …

Gender affirming hormone therapy (GAHT) is used by many transgender people to reduce
gender incongruence and improve psychological functioning. As GAHT shares many …

The growing number of people who identify themselves as transgender has gained
increased attention in recent years and will certainly impact personalized clinical practices …

Highlights•Feminizing gender-affirming hormone therapy (fGAHT) reduces gender
dysphoria.•fGAHT may increase cardiovascular (CV) mortality and certain adverse CV …

In addition to primary reproductive functions, gonadal hormones play an important role in an
array of neural mechanisms across the human lifespan. The ageing-related decline in their …

Background While extant literature clearly illustrates the negative experiences of
transgender and gender-diverse (TGD) people, the intersection between TGD identity and …

Background Cognitive functioning can be negatively influenced by age, cardiovascular risk
(CVR) and mental health challenges, and sex-hormones can have neuroprotective effects …

Transgender older adults have a long history of exclusion that shapes current experiences
with social services. However, scant gerontological research uses archival data, which can …

The objective of this research work was to analyze the psychological factors that are present
in gender dysphoria in adolescents, due to the importance of approaching psychological …

Women have greater risk than men for poor cognitive aging; however, by treating the whole
person, including genetics, lifestyle, and social environment, clinicians have an opportunity …