Heart failure with preserved ejection fraction: a review
MM Redfield, BA Borlaug - Jama, 2023 - jamanetwork.com
Importance Heart failure with preserved ejection fraction (HFpEF), defined as HF with an EF
of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 …
of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 …
Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …
Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial
Background Placement of an interatrial shunt device reduces pulmonary capillary wedge
pressure during exercise in patients with heart failure and preserved or mildly reduced …
pressure during exercise in patients with heart failure and preserved or mildly reduced …
Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …
to the rapidly increased prevalence of overweight and obesity. To this point …
From systemic inflammation to myocardial fibrosis: the heart failure with preserved ejection fraction paradigm revisited
WJ Paulus, MR Zile - Circulation research, 2021 - Am Heart Assoc
In accordance with the comorbidity-inflammation paradigm, comorbidities and especially
metabolic comorbidities are presumed to drive development and severity of heart failure with …
metabolic comorbidities are presumed to drive development and severity of heart failure with …
Heart failure with preserved ejection fraction: heterogeneous syndrome, diverse preclinical models
Heart failure with preserved ejection fraction (HFpEF) represents one of the greatest
challenges facing cardiovascular medicine today. Despite being the most common form of …
challenges facing cardiovascular medicine today. Despite being the most common form of …
Diagnosis of heart failure with preserved ejection fraction among patients with unexplained dyspnea
YNV Reddy, DM Kaye, ML Handoko… - JAMA …, 2022 - jamanetwork.com
Importance Diagnosis of heart failure with preserved ejection fraction (HFpEF) among
dyspneic patients without overt congestion is challenging. Multiple diagnostic approaches …
dyspneic patients without overt congestion is challenging. Multiple diagnostic approaches …
Myocardial gene expression signatures in human heart failure with preserved ejection fraction
Background: Heart failure (HF) with preserved ejection fraction (HFpEF) constitutes half of all
HF but lacks effective therapy. Understanding of its myocardial biology remains limited …
HF but lacks effective therapy. Understanding of its myocardial biology remains limited …
Heart failure with preserved ejection fraction: mechanisms and treatment strategies
K Omote, FH Verbrugge… - Annual review of medicine, 2022 - annualreviews.org
Approximately half of all patients with heart failure (HF) have a preserved ejection fraction,
and the prevalence is growing rapidly given the aging population in many countries and the …
and the prevalence is growing rapidly given the aging population in many countries and the …
Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review
Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved
ejection fraction (HFpEF), the most common form of heart failure among older individuals …
ejection fraction (HFpEF), the most common form of heart failure among older individuals …