General anesthetics threaten cardiovascular stability by causing changes in cardiac
function, vascular reactivity, and cardiovascular reflexes and significantly alter distribution of …

Neurogenic pulmonary edema (NPE) is a life-threatening complication of central nervous
system (CNS) injuries. This review summarizes current knowledge about NPE etiology and …

Background Volatile anesthetics impair insulin secretion and glucose utilization; however,
the precise mechanism of action that underlies these effects is unknown. The authors …

The Impact of Four Different Classes of Anesthetics on the Mechanisms of Blood Pressure
Regulation in Normotensive and Spontaneo Page 1 PHYSIOLOGICAL RESEARCH • ISSN …

Large-conductance Ca2+-activated K+ (BK) channels are composed of pore-forming α-
subunits and accessory β1-subunits that modulate Ca2+ sensitivity. BK channels regulate …

There has been an explosive increase in the amount of interesting information about the
physiologic and pathophysiologic roles of nitric oxide in cardiovascular, nervous, and …

IMPLICATIONS: The results of this study indicate that propofol-mediated hyperpolarization in
vascular smooth muscle can be attributed to the activation of calcium-activated, adenosine …

Background Vascular contractility and blood pressure (BP) are regulated by soluble
guanylyl cyclase (sGC) and cyclic guanosine monophosphate (cGMP) pathway, which can …

The pronounced activation of sympathetic nervous system is a necessary prerequisite for the
development of neurogenic pulmonary edema (NPE) in rats with balloon compression of …

Background Recent evidence indicates that vascular adenosine triphosphate-sensitive
potassium (K (ATP)) channels in vascular smooth muscle cells are critical in the regulation of …