The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Exosomes in angiogenesis and anti-angiogenic therapy in cancers

W Olejarz, G Kubiak-Tomaszewska… - International Journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …

[HTML][HTML] Biomarkers of endothelial activation and dysfunction in cardiovascular diseases

J Zhang - Reviews in cardiovascular medicine, 2022 - imrpress.com
Endothelial activation and dysfunction is an important contributor to atherosclerosis,
cardiovascular diseases and cardiorenal syndrome. Endothelial dysfunction is also linked …

Leptin in atherosclerosis: focus on macrophages, endothelial and smooth muscle cells

P Raman, S Khanal - International journal of molecular sciences, 2021 - mdpi.com
Increasing adipose tissue mass in obesity directly correlates with elevated circulating leptin
levels. Leptin is an adipokine known to play a role in numerous biological processes …

Nanomaterials responsive to endogenous biomarkers for cardiovascular disease theranostics

C Wei, Z Jiang, C Li, P Li, Q Fu - Advanced Functional Materials, 2023 - Wiley Online Library
Cardiovascular disease (CVD) is the number one cause of death worldwide, which propels
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

AB Herman, D Tsitsipatis, C Anerillas… - The Journal of …, 2023 - Am Soc Clin Investig
Senescent vascular smooth muscle cells (VSMCs) accumulate in the vasculature with age
and tissue damage and secrete factors that promote atherosclerotic plaque vulnerability and …

Identification of HMOX1 as a critical ferroptosis-related gene in atherosclerosis

D Wu, Q Hu, Y Wang, M Jin, Z Tao… - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Ferroptosis is a novel form of programmed iron-dependent cell death. The ferroptosis-
related genes (FRGs) have been recognized as biomarkers for cancers. Increasing …

Tuning macrophages for atherosclerosis treatment

F Fang, C Xiao, C Li, X Liu, S Li - Regenerative Biomaterials, 2023 - academic.oup.com
Atherosclerosis is a chronic inflammatory vascular disease and a leading cause of death
worldwide. Macrophages play an important role in inflammatory responses, cell–cell …

Matrix metaloproteinases in vascular pathology

G Simões, T Pereira, A Caseiro - Microvascular Research, 2022 - Elsevier
Vascular diseases are the main cause of morbidity and mortality. The vascular extracellular
matrix (ECM) is essential in mechanical support, also regulating the cellular behavior …

Novel biomarkers of atherosclerotic vascular disease—Latest insights in the research field

CA Adam, DL Șalaru, C Prisacariu, DTM Marcu… - International journal of …, 2022 - mdpi.com
The atherosclerotic vascular disease is a cardiovascular continuum in which the main role is
attributed to atherosclerosis, from its appearance to its associated complications. The …