Epigenetics and depression

S Penner-Goeke, EB Binder - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …

[HTML][HTML] MicroRNA mediators of early life stress vulnerability to depression and suicidal behavior

L Allen, Y Dwivedi - Molecular psychiatry, 2020 - nature.com
Childhood environment can have a profound impact on brain structure and function.
Epigenetic mechanisms have been shown to play a critical role in adaptive and maladaptive …

Exosomes from patients with major depression cause depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis

ZX Wei, GJ Xie, X Mao, XP Zou, YJ Liao… - …, 2020 - nature.com
Exosomal microRNAs (miRNAs) have been suggested to participate in the pathogenesis of
neuropsychiatric diseases, but their role in major depressive disorder (MDD) is unknown …

Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression

YY van der Zee, LMT Eijssen, P Mews… - Molecular …, 2022 - nature.com
Major depressive disorder (MDD) is the leading cause of disability worldwide. There is an
urgent need for objective biomarkers to diagnose this highly heterogeneous syndrome …

[HTML][HTML] CircDYM ameliorates depressive-like behavior by targeting miR-9 to regulate microglial activation via HSP90 ubiquitination

Y Zhang, L Du, Y Bai, B Han, C He, L Gong… - Molecular …, 2020 - nature.com
Circular RNAs (circRNAs), highly expressed in the central nervous system, are involved in
various regulatory processes and implicated in some pathophysiology. However, the …

[HTML][HTML] Epigenetic regulations in neuropsychiatric disorders

JN Kuehner, EC Bruggeman, Z Wen, B Yao - Frontiers in genetics, 2019 - frontiersin.org
Precise genetic and epigenetic spatiotemporal regulation of gene expression is critical for
proper brain development, function and circuitry formation in the mammalian central nervous …

Toll-like receptor signaling in depression

LK Figueroa-Hall, MP Paulus, J Savitz - Psychoneuroendocrinology, 2020 - Elsevier
Depression is one of the most prevalent, disabling, and costly mental illnesses currently
affecting over 300 million people worldwide. A subset of depressed patients display …

[HTML][HTML] The relationship between psychological health and social support: Evidence from physicians in China

J Sun, R Sun, Y Jiang, X Chen, Z Li, Z Ma, J Wei, C He… - Plos one, 2020 - journals.plos.org
Background The psychological health (PH) of doctors affects the quality of medical service
and is related to the safety of patients. The serious problems with the doctor-patient …

[HTML][HTML] Non-coding RNAs in depression: Promising diagnostic and therapeutic biomarkers

Y Shi, Q Wang, R Song, Y Kong, Z Zhang - EBioMedicine, 2021 - thelancet.com
Abstract Non-coding RNAs (ncRNAs), including microRNAs, circular RNAs, and long non-
coding RNAs, are important regulators of normal biological processes and their abnormal …

Bivalve molluscs as bioindicators of multiple stressors in the marine environment: recent advances

A Chahouri, B Yacoubi, A Moukrim… - Continental Shelf Research, 2023 - Elsevier
Ecosystems around the world are facing challenging issue in pollution management and
ocean services for the coastal community. Population growth in coastal areas, coupled with …