Mesenchymal stem cells (MSC) hold great potential for regenerative medicine because of
their ability for self-renewal and differentiation into tissue-specific cells such as osteoblasts …

Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …

Increased use of reconstruction procedures in orthopedics, due to trauma, tumor, deformity,
degeneration and an aging population, has caused a blossom, not only in surgical …

Mesenchymal stromal cells (MSCs) secrete paracrine factors that play crucial roles during
tissue regeneration. Whether this paracrine function is influenced by the properties of …

Tissue engineering is promising to meet the increasing need for bone regeneration.
Nanostructured calcium phosphate (CaP) biomaterials/scaffolds are of special interest as …

Mesenchymal stromal cells (MSCs) are currently being investigated in numerous clinical
trials of tissue repair and various immunological disorders based on their ability to secrete …

Osteoarthritis is a degenerative disease of joints with destruction of articular cartilage
associated with subchondral bone hypertrophy and inflammation. OA is the leading cause of …

Postmenopausal osteoporosis is the most common bone disease, associated with low bone
mineral density (BMD) and pathological fractures which lead to significant morbidity. It is …

Advanced bioceramics have played integral roles in treatment modalities for damaged or
diseased human joints and osseous defects. This paper reviews the uses and properties of …

Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …