Exosomes, as therapeutically relevant cell-secreted extracellular vesicles, have attracted
enormous interest because they participate in intercellular communication and facilitate …

Sports medicine is generally associated with soft tissue injuries including muscle injuries,
meniscus and ligament injuries, tendon ruptures, tendinopathy, rotator cuff tears, and tendon …

Tendon injuries are common debilitating musculoskeletal diseases with high treatment
expenditure in sports medicine. The development of tendon-biomimetic scaffolds may be …

The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa)
remains controversial. Previously, we found that plasma exosomal miR-375 is significantly …

Background Melanoma is the most malignant skin tumor and is difficult to cure with the
alternative treatments of chemotherapy, biotherapy, and immunotherapy. Our previous study …

Both acute and chronic tendon injuries are disabling sports medicine problems with no
effective treatment at present. Sustained oxidative stress has been suggested as the major …

Tendon injury is a tricky and prevalent motor system disease, leading to compromised daily
activity and disability. Insufficient regenerative capability and dysregulation of immune …

Background Tendon derived stem cells (TDSCs) have proven to be effective in tendon repair
by secreting paracrine factors, which modulate the function of resident cells and …

Wound healing is a complex and prolonged process that remains a significant challenge in
clinical practice. Exosomes, a type of nanoscale extracellular vesicles naturally secreted by …

Graft healing after anterior cruciate ligament reconstruction (ACLR) involves slow biological
processes, and various types of biological modulations have been explored to promote …