Animal models are essential for understanding the biological factors that contribute to drug
and alcohol addiction and discovering new pharmacotherapies to treat these disorders …

The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons.
Dysfunctions of dopaminergic circuits are observed in drug addiction and obsessive …

Many components of ethanol addiction such as reinforcement, withdrawal, extinction, and
relapse are known to involve glutamate transmission. NAC could counteract glutamatergic …

A robust body of research has shown that traumatic experiences occurring during critical
developmental periods of childhood when neuronal plasticity is high increase risks for a …

The profile of brain structural dysmorphology of individuals with Alcohol Use Disorders
(AUD) involves disruption of the limbic system. In vivo imaging studies report hippocampal …

Abstract Opioid Use Disorder (OUD) is a global epidemic also affecting women of
reproductive age. A standard form of pharmacological treatment for OUD is Opioid …

Recent advancements in technology have enabled researchers to probe the brain with the
greater region, cell, and receptor specificity. These developments have allowed for a more …

Day-level drinking motives are associated with intensity of drinking and occurrence of
negative consequences. However, little is known about how day-level drinking motives …

Binge drinking is characterized by bouts of high-intensity alcohol intake and is associated
with an array of health-related harms. Even though the transition from occasional impulsive …

Abstract The neurotrophin Brain-Derived Neurotrophic Factor (BDNF) has been implicated
in a number of neuropsychiatric disorders, including alcohol use disorder. Studies have …