This document was written with the intent to be a complete reference at the time of
publication on the topic of managing hypertension in the elderly. Given the length of the …

In the United States, 8 million adults have peripheral artery disease (PAD), a number that is
likely to escalate as the population ages. 1–3 Lower-extremity PAD is a component of …

The vascular network delivers oxygen (O2) and nutrients to all cells within the body. It is
therefore not surprising that O2 availability serves as a primary regulator of this complex …

Peripheral artery disease (PAD) has a huge social and economic burden and is an
important contributor to the global health burden. Sex differences in PAD are apparent, with …

Background: Critical limb ischemia (CLI) morbidity and mortality rates have historically been
disproportionately higher than for other atherosclerotic diseases, however, recent trends …

Background—Central obesity is associated with peripheral arterial disease, suggesting that
ectopic fat depots may be associated with localized diseases of the aorta and lower …

Patients with intermittent claudication carry a high risk for cardiovascular complications. The
TransAtlantic Inter-Society Consensus (TASC) Group estimated a five-year overall mortality …

Abstract Background and aims The Mediterranean Diet (MedD) is considered a very healthy
diet useful in the prevention of cardiovascular disease. The present study aims to evaluate …

TDP-43 proteinopathy is strongly implicated in the pathogenesis of amyotrophic lateral
sclerosis and related neurodegenerative disorders. Whether TDP-43 neurotoxicity is caused …

Peripheral arterial disease (PAD) is an increasingly recognized disorder that is associated
with functional impairment, quality-of-life deterioration, increased risk of cardiovascular …