Cardiovascular disease is common in patients with diabetes and is a significant contributor
to the high mortality rates associated with diabetes. Heart failure is common in diabetic …

Diabetes mellitus is one of the most common chronic diseases across the world.
Cardiovascular complication is the major morbidity and mortality among the diabetic …

OBJECTIVE To elucidate the molecular basis for mitochondrial dysfunction, which has been
implicated in the pathogenesis of diabetes complications. RESEARCH DESIGN AND …

Rationale: Creatine is thought to be involved in the spatial and temporal buffering of ATP in
energetic organs such as heart and skeletal muscle. Creatine depletion affects force …

Red and white muscles are faced with very different energetic demands. However, it is
unclear whether relative mitochondrial protein expression is different between muscle types …

The concentration of mitochondrial oxidative phosphorylation complexes (MOPCs) is tuned
to the maximum energy conversion requirements of a given tissue; however, whether the …

Administration of high doses of fluoride (F) can alter glucose homeostasis and lead to insulin
resistance (IR). This study determined the profile of protein expression in the gastrocnemius …

Muscle represents a large fraction of the human body mass. It is an extremely
heterogeneous tissue featuring in its contractile structure various proportions of heavy-and …

Insulin plays pivotal role in cellular fuel metabolism in skeletal muscle. Despite being the
primary site of energy metabolism, the underlying mechanism on how insulin deficiency …

Cardiovascular disease is the leading cause of diabetes-related morbidity and mortality. It is
widely accepted that heart failure risk is increased in diabetic patients even after adjusting …