[HTML][HTML] Targeting gut microbiota and metabolism as the major probiotic mechanism-An evidence-based review

T Ma, X Shen, X Shi, HA Sakandar, K Quan, Y Li… - Trends in Food Science …, 2023 - Elsevier
Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …

[HTML][HTML] The intestinal microbiota and metabolites in the gut-kidney-heart axis of chronic kidney disease

Y Huang, W Xin, J Xiong, M Yao, B Zhang… - Frontiers in …, 2022 - frontiersin.org
Emerging evidences demonstrate the involvement of gut microbiota in the progression of
chronic kidney disease (CKD) and CKD-associated complications including cardiovascular …

[HTML][HTML] Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery

J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …

Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation

Z Tian, Y Zhang, Z Zheng, M Zhang, T Zhang, J Jin… - Cell host & …, 2022 - cell.com
Abdominal aortic aneurysm (AAA) is an insidious and lethal vascular disease that lacks
effective nonsurgical interventions. Gut microbiota dysbiosis plays key roles in many …

Biomimetic Bacteriophage‐Like Particles Formed from Probiotic Extracts and NO Donors for Eradicating Multidrug‐Resistant Staphylococcus aureus

C Gong, W Guan, X Liu, Y Zheng, Z Li… - Advanced …, 2022 - Wiley Online Library
Effectively clearing multidrug‐resistant bacteria through nonantibiotic treatments is crucial
for the recovery of infected tissues in favorable biological environments. Herein, a thermally …

Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy

L Luo, J Luo, Y Cai, M Fu, W Li, L Shi, J Liu… - Pharmacological …, 2022 - Elsevier
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few
treatment options that prevent the progressive loss of renal function are available. Studies …

Local and systemic effects of microbiome‐derived metabolites

I Spivak, L Fluhr, E Elinav - EMBO reports, 2022 - embopress.org
Commensal microbes form distinct ecosystems within their mammalian hosts, collectively
termed microbiomes. These indigenous microbial communities broadly expand the genomic …

iProbiotics: a machine learning platform for rapid identification of probiotic properties from whole-genome primary sequences

Y Sun, H Li, L Zheng, J Li, Y Hong… - Briefings in …, 2022 - academic.oup.com
Lactic acid bacteria consortia are commonly present in food, and some of these bacteria
possess probiotic properties. However, discovery and experimental validation of probiotics …

[HTML][HTML] The potential benefits and controversies of probiotics use in patients at different stages of chronic kidney disease

N Tian, L Li, JKC Ng, PKT Li - Nutrients, 2022 - mdpi.com
The therapeutic modulation of the gut microbiome has been suggested to be one of the tools
in the integrated management of chronic kidney disease (CKD) in recent years …

Gut microbiota‐derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling

LW Liu, Y Xie, GQ Li, T Zhang, YH Sui… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Gut microbiota dysbiosis induced by acute pancreatitis (AP)
exacerbates pancreatic injury and systemic inflammatory responses. The alleviation of gut …