The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …
Current state of Alzheimer's fluid biomarkers
JL Molinuevo, S Ayton, R Batrla, MM Bednar… - Acta …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …
heterogeneous pathophysiology. The number of people living with AD is predicted to …
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
C Bergamaschi, E Terpos, M Rosati, M Angel, J Bear… - Cell reports, 2021 - cell.com
Early responses to vaccination are important for shaping both humoral and cellular
protective immunity. Dissecting innate vaccine signatures may predict immunogenicity to …
protective immunity. Dissecting innate vaccine signatures may predict immunogenicity to …
The vaginal microbiome and preterm birth
JM Fettweis, MG Serrano, JP Brooks, DJ Edwards… - Nature medicine, 2019 - nature.com
The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in
the frequency of preterm birth among populations within countries, and women of African …
the frequency of preterm birth among populations within countries, and women of African …
The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans
Silicone is widely used in chronic implants and is generally perceived to be safe. However,
textured breast implants have been associated with immune-related complications …
textured breast implants have been associated with immune-related complications …
Impact of mRNA chemistry and manufacturing process on innate immune activation
J Nelson, EW Sorensen, S Mintri, AE Rabideau… - Science …, 2020 - science.org
Messenger RNA (mRNA) represents an attractive therapeutic modality for potentially a wide
range of clinical indications but requires uridine chemistry modification and/or tuning of the …
range of clinical indications but requires uridine chemistry modification and/or tuning of the …
The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
The chemokine superfamily revisited
A Zlotnik, O Yoshie - Immunity, 2012 - cell.com
The chemokine superfamily consists of a large number of ligands and receptors. At first
glance, this family appears redundant and their ligand-receptor relationships promiscuous …
glance, this family appears redundant and their ligand-receptor relationships promiscuous …
The systematic effect of mesenchymal stem cell therapy in critical COVID-19 patients: a prospective double controlled trial
G Adas, Z Çukurova, KK Yasar, R Yilmaz… - Cell …, 2021 - journals.sagepub.com
The aim of this clinical trial was to control the cytokine storm by administering mesenchymal
stem cells (MSCs) to critically-ill COVID-19 patients, to evaluate the healing effect, and to …
stem cells (MSCs) to critically-ill COVID-19 patients, to evaluate the healing effect, and to …
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity
R Edahiro, Y Shirai, Y Takeshima, S Sakakibara… - Nature …, 2023 - nature.com
Mechanisms underpinning the dysfunctional immune response in severe acute respiratory
syndrome coronavirus 2 infection are elusive. We analyzed single-cell transcriptomes and T …
syndrome coronavirus 2 infection are elusive. We analyzed single-cell transcriptomes and T …