Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy
M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
Polymersome Membrane Engineering with Active Targeting or Controlled Permeability for Responsive Drug Delivery
A Kayani, A Raza, J Si, D Dutta, Q Zhou… - Biomacromolecules, 2023 - ACS Publications
Polymersomes have been extensively investigated for drug delivery as nanocarriers for two
decades due to a series of advantages including high stability under physiological …
decades due to a series of advantages including high stability under physiological …
Biomimetic dendritic polymeric microspheres induce enhanced T cell activation and expansion for adoptive tumor immunotherapy
A variety of bioactive materials are currently developed to expand T cells ex vivo for adoptive
T cell immunotherapy, also known as called artificial antigen-presenting cells (aAPCs) …
T cell immunotherapy, also known as called artificial antigen-presenting cells (aAPCs) …
[HTML][HTML] Nanocarriers for delivery of siRNA as gene silencing mediator
A Morales-Becerril, L Aranda-Lara, K Isaac-Olivé… - EXCLI …, 2022 - ncbi.nlm.nih.gov
The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …
Block Length‐Dependent Protein Fouling on Poly (2‐oxazoline)‐Based Polymersomes: Influence on Macrophage Association and Circulation Behavior
Polymersomes are vesicular structures self‐assembled from amphiphilic block copolymers
and are considered an alternative to liposomes for applications in drug delivery …
and are considered an alternative to liposomes for applications in drug delivery …
[HTML][HTML] Polymersomes with splenic avidity target red pulp myeloid cells for cancer immunotherapy
AC Wauters, JF Scheerstra, MMT van Leent… - Nature …, 2024 - nature.com
Regulating innate immunity is an emerging approach to improve cancer immunotherapy.
Such regulation requires engaging myeloid cells by delivering immunomodulatory …
Such regulation requires engaging myeloid cells by delivering immunomodulatory …
Preparation of polymersomes from synthesized hyaluronic acid-graft-poly (ε-caprolactone) copolymers for drug delivery to the brain
The application of amphiphilic block copolymer for drug delivery has received immense
attention in recent years. Polymersomes are favorable types of polymeric systems that can …
attention in recent years. Polymersomes are favorable types of polymeric systems that can …
Differences in human plasma protein interactions between various polymersomes and stealth liposomes as observed by fluorescence correlation spectroscopy
A significant factor hindering the clinical translation of polymersomes as vesicular
nanocarriers is the limited availability of comparative studies detailing their interaction with …
nanocarriers is the limited availability of comparative studies detailing their interaction with …
[HTML][HTML] Current perspectives on synthetic compartments for biomedical applications
L Heuberger, M Korpidou, OM Eggenberger… - International Journal of …, 2022 - mdpi.com
Nano-and micrometer-sized compartments composed of synthetic polymers are designed to
mimic spatial and temporal divisions found in nature. Self-assembly of polymers into …
mimic spatial and temporal divisions found in nature. Self-assembly of polymers into …
pH and ROS Responsiveness of Polymersome Nanovaccines for Antigen and Adjuvant Codelivery: An In Vitro and In Vivo Comparison
E Jäger, O Ilina, Y Dölen, M Valente… - …, 2024 - ACS Publications
The antitumor immunity can be enhanced through the synchronized codelivery of antigens
and immunostimulatory adjuvants to antigen-presenting cells, particularly dendritic cells …
and immunostimulatory adjuvants to antigen-presenting cells, particularly dendritic cells …