The muscle extracellular matrix (ECM) forms a complex network of collagens, proteoglycans,
and other proteins that produce a favorable environment for muscle regeneration, protect the …

The glycosaminoglycan hyaluronan (HA) is a key component of the microenvironment
surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass …

Hyaluronan (HA) has complex biological roles that have catalyzed clinical interest in several
fields of medicine. In this narrative review, we provide an overview of HA aggregation, also …

Background: This study combined neuromechanical modeling analysis, muscle tone
measurement from mechanical indentation and electrical impedance myography to assess …

Spasticity is one component of the upper motor neuron (UMN) syndrome resulting from a
multitude of neurologic conditions, such as stroke, brain injury, spinal cord injury, multiple …

Hyaluronan (HA) is a glycosaminoglycan that consists of single‐chain polymers of
disaccharide units of glucuronic acid and N‐acetylglucosamine. It is a chief constituent of the …

Individuals post-stroke experience persisting gait deficits due to altered joint mechanics,
known clinically as spasticity, hypertonia, and paresis. In engineering, these concepts are …

The assessment of soft tissue stiffness is important to evaluate many neuromusculoskeletal
conditions. Several tools have been proposed for the assessment of stiffness, but …

The purpose of this study was to provide imaging evidence of increased glycosaminoglycan
(GAG) content in patients with post-stroke muscle stiffness; and to determine the effect of …

Hyaluronate lyase (HA lyase) has potential in the industrial processing of hyaluronan. In this
study, HylP, an HA lyase from Streptococcus pyogenes phage (SPB) was successfully …