[HTML][HTML] Exosome-derived microRNAs of human milk and their effects on infant health and development

BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …

[HTML][HTML] Exosomes of pasteurized milk: potential pathogens of Western diseases

BC Melnik, G Schmitz - Journal of translational medicine, 2019 - Springer
Milk consumption is a hallmark of western diet. According to common believes, milk
consumption has beneficial effects for human health. Pasteurization of cow's milk protects …

[HTML][HTML] Milk's role as an epigenetic regulator in health and disease

BC Melnik, G Schmitz - Diseases, 2017 - mdpi.com
It is the intention of this review to characterize milk's role as an epigenetic regulator in health
and disease. Based on translational research, we identify milk as a major epigenetic …

[HTML][HTML] Breast milk and solid food shaping intestinal immunity

SM Parigi, M Eldh, P Larssen, S Gabrielsson… - Frontiers in …, 2015 - frontiersin.org
After birth, the intestinal immune system enters a critical developmental stage, in which
tolerogenic and pro-inflammatory cells emerge to contribute to the overall health of the host …

[HTML][HTML] Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation

BC Melnik, SM John, P Carrera-Bastos… - Clinical and translational …, 2016 - Springer
Background Breastfeeding has protective effects for the development of allergies and atopy.
Recent evidence underlines that consumption of unboiled farm milk in early life is a key …

[HTML][HTML] Cow's milk allergy in Dutch children: an epigenetic pilot survey

NCM Petrus, P Henneman, A Venema, A Mul… - Clinical and translational …, 2016 - Springer
Background Cow's milk allergy (CMA) is a common disease in infancy. Early environmental
factors are likely to contribute to CMA. It is known that epigenetic gene regulation can be …

Breast Milk-Transforming Growth Factor-β2 Specifically Attenuates IL-1β-Induced Inflammatory Responses in the Immature Human Intestine via an SMAD6- and ERK …

S Rautava, NN Nanthakumar, A Dubert-Ferrandon… - Neonatology, 2011 - karger.com
Background: Breast milk is known to protect the infant against infectious and immuno-
inflammatory diseases, but the mechanisms of this protection are poorly understood …

Increased maternal BMI is associated with infant wheezing in early life: a prospective cohort study

A De Vries, RM Reynolds, JR Seckl… - … origins of health and …, 2014 - cambridge.org
Rates of obesity are increasing in women of child bearing age with negative impacts on
maternal and offspring health. Emerging evidence suggests in utero origins of respiratory …

Programming Molecules in Early Life

ÖN Şahin, DD Briana - Breastfeeding and Metabolic Programming, 2023 - Springer
Children whose mothers suffered from obesity, diabetes mellitus, or who had feeding
difficulties face an increased risk of metabolic disorders, research has shown [1, 2] …

The Part Breast Milk Plays in Epigenetic Programming

ÖN Şahin - Breastfeeding and Metabolic Programming, 2023 - Springer
For mammals, following birth, the source of their entire nutrition is milk. Milk provides a
transition between placental nutrition and an adult diet. Weaning is the stage of moving onto …