Novel tumor necrosis factor-α induced protein eight (TNFAIP8/TIPE) family: Functions and downstream targets involved in cancer progression

G Padmavathi, K Banik, J Monisha, D Bordoloi… - Cancer letters, 2018 - Elsevier
The tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8/TIPE) family is a death
effector domain (DED)-containing protein family with four identified members: TNFAIP8 …

Tumour necrosis factor alpha (TNF-α) and oral squamous cell carcinoma

G Brierly, A Celentano, O Breik, E Moslemivayeghan… - Cancers, 2023 - mdpi.com
Simple Summary TNF-α is of interest in oral squamous cell carcinoma (OSCC), with its
demonstrated presence affecting both tumour and stromal inflammatory cells to enhance …

[HTML][HTML] TIPE regulates VEGFR2 expression and promotes angiogenesis in colorectal cancer

M Zhong, N Li, X Qiu, Y Ye, H Chen, J Hua… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Background: Metastasis is the leading cause of death in colorectal cancer (CRC) patients. It
is regulated mainly by tumor cell angiogenesis, and angiogenesis is caused by the binding …

TIPE family of proteins and its implications in different chronic diseases

D Bordoloi, K Banik, B Shabnam… - International journal of …, 2018 - mdpi.com
The tumor necrosis factor-α-induced protein 8-like (TIPE/TNFAIP8) family is a recently
identified family of proteins that is strongly associated with the regulation of immunity and …

Tumor necrosis factor alpha-induced proteins in malignant tumors: progress and prospects

F Guo, Y Yuan - OncoTargets and therapy, 2020 - Taylor & Francis
Tumor necrosis factor (TNF) is the first cytokine used in tumor biotherapy, but TNF-related
drugs are limited by the lack of specific targets. Tumor necrosis factor alpha-induced …

Oncogenic role of tumor necrosis factor α-induced protein 8 (TNFAIP8)

S Niture, X Dong, E Arthur, U Chimeh, SS Niture… - Cells, 2018 - mdpi.com
Tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8) is a founding member of the
TIPE family, which also includes TNFAIP8-like 1 (TIPE1), TNFAIP8-like 2 (TIPE2), and …

Ferroptosis‐Related lncRNA Signature Correlates with the Prognosis, Tumor Microenvironment, and Therapeutic Sensitivity of Esophageal Squamous Cell …

J Zhu, Y Zhao, G Wu, X Zhang, Q Chen… - Oxidative Medicine …, 2022 - Wiley Online Library
Esophageal squamous cell carcinoma (ESCC) is the most prevalent form of esophageal
cancer in China and is closely associated with malignant biological characteristics and poor …

[HTML][HTML] Tumor necrosis factor-α induced protein 8: pathophysiology, clinical significance, and regulatory mechanism

L Zhang, R Liu, Y Luan, Y Yao - International Journal of Biological …, 2018 - ncbi.nlm.nih.gov
Tumor necrosis factor-α-induced protein-8 (TNFAIP8) is the earliest discovered component
of TNFAIP8 family [tumor necrosis factor-α-induced protein-8 like (TIPE) family]. TNFAIP8 …

TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1

Y Pang, Y Zhao, Y Wang, X Wang, R Wang… - Journal of Experimental …, 2020 - Springer
Background Chemoresistance is emerging as a major barrier to successful treatment in
acute myeloid leukemia (AML), and evasion of apoptosis is among the fundamental …

Micro RNA‐9 inhibits the gastric cancer cell proliferation by targeting TNFAIP 8

HY Gao, FC Huo, HY Wang, DS Pei - Cell proliferation, 2017 - Wiley Online Library
Background and objectives Micro RNA‐9 is frequently dysregulated in many human
carcinoma types, including gastric cancer (GC). Previous studies demonstrated that the …