[HTML][HTML] Functional nanomaterials in peripheral nerve regeneration: scaffold design, chemical principles and microenvironmental remodeling

Y Qian, H Lin, Z Yan, J Shi, C Fan - Materials Today, 2021 - Elsevier
Neuronal microenvironment imbalance is associated with successive and irreversible
pathophysiological changes and insufficient functional restoration after peripheral nerve …

The success and failure of the Schwann cell response to nerve injury

KR Jessen, R Mirsky - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin)
and myelin phenotypes, which are specialized to meet the needs of small and large …

Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

YS Choi, YY Hsueh, J Koo, Q Yang, R Avila… - Nature …, 2020 - nature.com
Bioresorbable electronic stimulators are of rapidly growing interest as unusual therapeutic
platforms, ie, bioelectronic medicines, for treating disease states, accelerating wound …

[HTML][HTML] Schwann cell functions in peripheral nerve development and repair

M Bosch-Queralt, R Fledrich, RM Stassart - Neurobiology of disease, 2023 - Elsevier
The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

The repair Schwann cell and its function in regenerating nerves

KR Jessen, R Mirsky - The Journal of physiology, 2016 - Wiley Online Library
Nerve injury triggers the conversion of myelin and non‐myelin (Remak) Schwann cells to a
cell phenotype specialized to promote repair. Distal to damage, these repair Schwann cells …

Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves

KR Jessen, P Arthur‐Farraj - Glia, 2019 - Wiley Online Library
Schwann cells respond to nerve injury by cellular reprogramming that generates cells
specialized for promoting regeneration and repair. These repair cells clear redundant …

Schwann cells: development and role in nerve repair

KR Jessen, R Mirsky, AC Lloyd - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Schwann cells develop from the neural crest in a well-defined sequence of events. This
involves the formation of the Schwann cell precursor and immature Schwann cells, followed …

Peripheral nerve regeneration: experimental strategies and future perspectives

A Faroni, SA Mobasseri, PJ Kingham… - Advanced drug delivery …, 2015 - Elsevier
Peripheral nerve injuries represent a substantial clinical problem with insufficient or
unsatisfactory treatment options. This review summarises all the events occurring after nerve …

Photosensitive and conductive hydrogel induced innerved bone regeneration for infected bone defect repair

X Jing, C Xu, W Su, Q Ding, B Ye, Y Su… - Advanced …, 2023 - Wiley Online Library
Repairing infected bone defects is a challenge in the field of orthopedics because of the
limited self‐healing capacity of bone tissue and the susceptibility of refractory materials to …

Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy

G Fumagalli, L Monza, G Cavaletti, R Rigolio… - Frontiers in …, 2021 - frontiersin.org
Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …