Clinical pharmacology in diuretic use

DH Ellison - Clinical Journal of the American Society of …, 2019 - journals.lww.com
Diuretics are among the most commonly prescribed drugs and, although effective, they are
often used to treat patients at substantial risk for complications, making it especially …

[HTML][HTML] Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

AA House, C Wanner, MJ Sarnak, IL Piña… - Kidney international, 2019 - Elsevier
The incidence and prevalence of heart failure (HF) and chronic kidney disease (CKD) are
increasing, and as such a better understanding of the interface between both conditions is …

New perspectives and future directions in the treatment of heart failure

P Pellicori, MJI Khan, FJ Graham, JGF Cleland - Heart Failure Reviews, 2020 - Springer
The management of heart failure has changed significantly over the last 30 years, leading to
improvements in the quality of life and outcomes, at least for patients with a substantially …

Comparative effects of furosemide and other diuretics in the treatment of heart failure: a systematic review and combined meta-analysis of randomized controlled trials

PS Eid, DA Ibrahim, AH Zayan, MMA Elrahman… - Heart Failure …, 2021 - Springer
Diuretics have an essential role in the management of heart failure (HF). However, each
drug has its own benefit and side effect. Side effects include fluid, electrolyte abnormalities …

Pharmacological interventions for heart failure in people with chronic kidney disease

M Lunney, M Ruospo, P Natale… - Cochrane Database …, 2020 - cochranelibrary.com
Background Approximately half of people with heart failure have chronic kidney disease
(CKD). Pharmacological interventions for heart failure in people with CKD have the potential …

Meta-analysis comparing torsemide versus furosemide in patients with heart failure

B Abraham, M Megaly, M Sous… - The American journal of …, 2020 - Elsevier
Although torsemide's oral bioavailability and half-life theoretically render it a more efficient
diuretic than furosemide, the clinical outcomes of torsemide compared with furosemide …

Torsemide versus furosemide and intermediate-term outcomes in patients with heart failure: an updated meta-analysis

JA Miles, BK Hanumanthu, K Patel… - Journal of …, 2019 - journals.lww.com
Aims Loop diuretics have become a mainstay of chronic heart failure management.
Furosemide and torsemide are the two most common loop diuretics; nevertheless, there is …

Optimizing guideline-directed medical therapies for heart failure with reduced ejection fraction during hospitalization

NM Dixit, S Shah, B Ziaeian, GC Fonarow, JJ Hsu - 2023 - escholarship.org
Heart failure remains a huge societal concern despite medical advancement, with an annual
direct cost of over $30 billion. While guideline-directed medical therapy (GDMT) is proven to …

Efficacy of oral torasemide in dogs with degenerative mitral valve disease and new onset congestive heart failure: The CARPODIEM study

B Besche, T Blondel, E Guillot… - Journal of Veterinary …, 2020 - Wiley Online Library
Background Torasemide is a potent loop diuretic with potential to treat congestive heart
failure (CHF) in dogs. Objective Evaluate the efficacy and safety of torasemide compared to …

Rate pressure product and the components of heart rate and systolic blood pressure in hospitalized heart failure patients with preserved ejection fraction: Insights from …

AK Verma, JL Sun, A Hernandez, JR Teerlink… - Clinical …, 2018 - Wiley Online Library
Background Heart rate and systolic blood pressure (SBP) are prognostic markers in heart
failure (HF) with reduced ejection fraction (HFrEF). Their combination in rate pressure …