Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …

The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

Intrarenal B cells in human renal allografts indicate transplant recipients with a poor
prognosis, but how these cells contribute to rejection is unclear. Here we show using single …

New biomarkers of early and late graft dysfunction are needed in renal transplant to improve
management of complications and prolong graft survival. A wide range of potential …

Apoptotic exosome-like vesicles (ApoExos) are a novel type of extracellular vesicle that
contribute to the propagation of inflammation at sites of vascular injury when released by …

The major medical advances in our knowledge of the human leukocyte antigen (HLA)
system have allowed us to uncover several gaps in our understanding of alloimmunity …

Endothelial cells have multifaceted interactions with the immune system, both as initiators
and targets of immune responses. In vivo, apoptotic endothelial cells release two types of …

The ability to personalize management for a given kidney transplant recipient and identify
treatments that will improve their long-term outcome remains a critical unmet need. Earlier …

Graft rejection remains the major obstacle after vascularized solid organ transplantation.
Endothelial cells, which form the interface between the transplanted graft and the host's …

Angiotensin II type 1 receptor antibodies (AT1R-Ab) are among the most investigated types
of non-HLA antibodies in kidney transplantation. Our aim is to provide an update regarding …