Background: Previous guidelines for the management of thyroid nodules and cancers were
geared toward adults. Compared with thyroid neoplasms in adults, however, those in the …

The retinoblastoma (RB) tumour suppressor gene is functionally inactivated in a broad
range of paediatric and adult cancers, and a plethora of cellular functions and partners have …

In order to search for sequence variants conferring risk of thyroid cancer we conducted a
genome-wide association study in 192 and 37,196 Icelandic cases and controls …

Background The expression of vascular endothelial growth factor (VEGF) is characteristic of
differentiated thyroid cancer and is associated with aggressive tumor behavior and a poor …

To search for sequence variants conferring risk of nonmedullary thyroid cancer, we focused
our analysis on 22 SNPs with a P< 5× 10− 8 in a genome-wide association study on levels …

The great majority of thyroid cancers are of the non-medullary type. Here we report findings
from a genome-wide association study of non-medullary thyroid cancer, including in total …

Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …

Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …

Context: Hurthle cell cancer (HCC) is an understudied cancer with poor prognosis.
Objective: Our objective was to elucidate the genomic foundations of HCC. Design and …

Background: Many studies on thyroid follicular tumors have reported the presence of
somatic mutations to three forms of RAS: HRAS, KRAS, and NRAS. However, the frequency …