[HTML][HTML] Management guidelines for children with thyroid nodules and differentiated thyroid cancer
L FrancisGary, G WaguespackSteven, J BauerAndrew… - Thyroid, 2015 - liebertpub.com
Background: Previous guidelines for the management of thyroid nodules and cancers were
geared toward adults. Compared with thyroid neoplasms in adults, however, those in the …
geared toward adults. Compared with thyroid neoplasms in adults, however, those in the …
Cellular mechanisms of tumour suppression by the retinoblastoma gene
DL Burkhart, J Sage - Nature Reviews Cancer, 2008 - nature.com
The retinoblastoma (RB) tumour suppressor gene is functionally inactivated in a broad
range of paediatric and adult cancers, and a plethora of cellular functions and partners have …
range of paediatric and adult cancers, and a plethora of cellular functions and partners have …
Common variants on 9q22. 33 and 14q13. 3 predispose to thyroid cancer in European populations
J Gudmundsson, P Sulem, DF Gudbjartsson… - Nature …, 2009 - nature.com
In order to search for sequence variants conferring risk of thyroid cancer we conducted a
genome-wide association study in 192 and 37,196 Icelandic cases and controls …
genome-wide association study in 192 and 37,196 Icelandic cases and controls …
[HTML][HTML] Motesanib diphosphate in progressive differentiated thyroid cancer
SI Sherman, LJ Wirth, JP Droz… - … England Journal of …, 2008 - Mass Medical Soc
Background The expression of vascular endothelial growth factor (VEGF) is characteristic of
differentiated thyroid cancer and is associated with aggressive tumor behavior and a poor …
differentiated thyroid cancer and is associated with aggressive tumor behavior and a poor …
Discovery of common variants associated with low TSH levels and thyroid cancer risk
J Gudmundsson, P Sulem, DF Gudbjartsson… - Nature …, 2012 - nature.com
To search for sequence variants conferring risk of nonmedullary thyroid cancer, we focused
our analysis on 22 SNPs with a P< 5× 10− 8 in a genome-wide association study on levels …
our analysis on 22 SNPs with a P< 5× 10− 8 in a genome-wide association study on levels …
A genome-wide association study yields five novel thyroid cancer risk loci
J Gudmundsson, G Thorleifsson, JK Sigurdsson… - Nature …, 2017 - nature.com
The great majority of thyroid cancers are of the non-medullary type. Here we report findings
from a genome-wide association study of non-medullary thyroid cancer, including in total …
from a genome-wide association study of non-medullary thyroid cancer, including in total …
Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma—a meta‐analysis
HG Vuong, AMA Altibi, UNP Duong… - Clinical …, 2017 - Wiley Online Library
Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …
Molecular alterations in thyroid cancer: from bench to clinical practice
E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …
Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy
I Ganly, J Ricarte Filho, S Eng… - The Journal of …, 2013 - academic.oup.com
Context: Hurthle cell cancer (HCC) is an understudied cancer with poor prognosis.
Objective: Our objective was to elucidate the genomic foundations of HCC. Design and …
Objective: Our objective was to elucidate the genomic foundations of HCC. Design and …
The Associations Between RAS Mutations and Clinical Characteristics in Follicular Thyroid Tumors: New Insights from a Single Center and a Large Patient Cohort
M Fukahori, A Yoshida, H Hayashi, M Yoshihara… - Thyroid, 2012 - liebertpub.com
Background: Many studies on thyroid follicular tumors have reported the presence of
somatic mutations to three forms of RAS: HRAS, KRAS, and NRAS. However, the frequency …
somatic mutations to three forms of RAS: HRAS, KRAS, and NRAS. However, the frequency …