Functional hydrogels for the treatment of myocardial infarction

T Wu, W Liu - NPG Asia Materials, 2022 - nature.com
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it
leads to necrosis of numerous cardiomyocytes (CMs), left ventricle dilation, and cardiac …

Durable immunomodulatory nanofiber niche for the functional remodeling of cardiovascular tissue

Y Liu, L Wang, Z Liu, Y Kang, T Chen, C Xu, T Zhu - ACS nano, 2023 - ACS Publications
Functional remodeling and prolonged anti-inflammatory responses are both vital for
repairing damage in the cardiovascular system. Although these aspects have each been …

An off-the-shelf bioadhesive patch for sutureless repair of gastrointestinal defects

J Wu, H Yuk, TL Sarrafian, CF Guo… - Science translational …, 2022 - science.org
Surgical sealing and repair of injured and resected gastrointestinal (GI) organs are critical
requirements for successful treatment and tissue healing. Despite being the standard of …

An overview of the molecular mechanisms associated with myocardial ischemic injury: state of the art and translational perspectives

L Schirone, M Forte, L D'Ambrosio, V Valenti… - Cells, 2022 - mdpi.com
Cardiovascular disease is the leading cause of death in western countries. Among
cardiovascular diseases, myocardial infarction represents a life-threatening condition …

New mechanical markers for tracking the progression of myocardial infarction

Z Chang, J Zhang, Y Liu, H Gao, GK Xu - Nano Letters, 2023 - ACS Publications
The mechanical properties of soft tissues can often be strongly correlated with the
progression of various diseases, such as myocardial infarction (MI). However, the dynamic …

Polysaccharide-based biomaterials in tissue engineering: a review

M Jin, J Shi, W Zhu, H Yao, DA Wang - Tissue Engineering Part B …, 2021 - liebertpub.com
In addition to proteins and nucleic acids, polysaccharides are an important type of
biomacromolecule widely distributed in plants, animals, and microorganisms …

Coadministration of an adhesive conductive hydrogel patch and an injectable hydrogel to treat myocardial infarction

T Wu, C Cui, Y Huang, Y Liu, C Fan… - … applied materials & …, 2019 - ACS Publications
Over the past decade, tissue-engineering strategies, mainly involving injectable hydrogels
and epicardial biomaterial patches, have been pursued to treat myocardial infarction …

A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair

X Song, X Wang, J Zhang, S Shen, W Yin, G Ye… - Biomaterials, 2021 - Elsevier
Conductive hydrogel is a potential therapeutic tool to treat damaged heart muscles in
myocardial infarction (MI). However, it is still a quite challenge to optimize the fabrication of a …

Underwater and wet adhesion strategies for hydrogels in biomedical applications

HY Yuen, HP Bei, X Zhao - Chemical Engineering Journal, 2022 - Elsevier
Hydrogel is a class of biomaterials that is widely adopted in tissue engineering due to its
versatility and biocompatibility in mimicking natural tissue properties. For these hydrogels …

Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery

D Zhu, J Hou, M Qian, D Jin, T Hao, Y Pan… - Nature …, 2021 - nature.com
Nitric oxide (NO) is a short-lived signaling molecule that plays a pivotal role in
cardiovascular system. Organic nitrates represent a class of NO-donating drugs for treating …