An intrapericardial injectable hydrogel patch for mechanical–electrical coupling with infarcted myocardium

C Yu, Z Yue, M Shi, L Jiang, S Chen, M Yao, Q Yu… - ACS …, 2022 - ACS Publications
Although hydrogel-based patches have shown promising therapeutic efficacy in myocardial
infarction (MI), synergistic mechanical, electrical, and biological cues are required to restore …

Self-adhesive hydrogels for tissue engineering

Y Yi, C Xie, J Liu, Y Zheng, J Wang, X Lu - Journal of Materials …, 2021 - pubs.rsc.org
Hydrogels consisting of a three-dimensional hydrophilic network of biocompatible polymers
have been widely used in tissue engineering. Owing to their tunable mechanical properties …

Conductive biomaterials for cardiac repair: A review

Y Li, L Wei, L Lan, Y Gao, Q Zhang, H Dawit, J Mao… - Acta biomaterialia, 2022 - Elsevier
Myocardial infarction (MI) is one of the fatal diseases in humans. Its incidence is constantly
increasing annually all over the world. The problem is accompanied by the limited …

Diatom-inspired bionic hydrophilic polysaccharide adhesive for rapid sealing hemostasis

X Sun, N Li, C Su, Y Mu, X Cong, Z Cao, X Wang… - ACS …, 2023 - ACS Publications
Diatoms are typical marine biofouling organisms that secrete extracellular polymers (EPS) to
achieve strong underwater adhesion. Here, we report a diatom-inspired bionic hydrophilic …

A perfusable, multifunctional epicardial device improves cardiac function and tissue repair

S Huang, D Lei, Q Yang, Y Yang, C Jiang, H Shi… - Nature medicine, 2021 - nature.com
Despite advances in technologies for cardiac repair after myocardial infarction (MI), new
integrated therapeutic approaches still need to be developed. In this study, we designed a …

Next generation of heart regenerative therapies: progress and promise of cardiac tissue engineering

MF Tenreiro, AF Louro, PM Alves… - NPJ Regenerative …, 2021 - nature.com
The adult heart is a vital and highly specialized organ of the human body, with limited
capability of self-repair and regeneration in case of injury or disease. Engineering …

Bioengineering approaches to treat the failing heart: from cell biology to 3D printing

M Yadid, H Oved, E Silberman, T Dvir - Nature Reviews Cardiology, 2022 - nature.com
Successfully engineering a functional, human, myocardial pump would represent a
therapeutic alternative for the millions of patients with end-stage heart disease and provide …

Ventricular tachyarrhythmia treatment and prevention by subthreshold stimulation with stretchable epicardial multichannel electrode array

SH Sunwoo, MJ Cha, SI Han, H Kang, YS Cho… - Science …, 2023 - science.org
The implantable cardioverter-defibrillator (ICD) is an effective method to prevent sudden
cardiac death in high-risk patients. However, the transvenous lead is incompatible with large …

[HTML][HTML] A paintable and adhesive hydrogel cardiac patch with sustained release of ANGPTL4 for infarcted heart repair

M Lee, YS Kim, J Park, G Choe, S Lee, BG Kang… - Bioactive Materials, 2024 - Elsevier
The infarcted heart undergoes irreversible pathological remodeling after reperfusion
involving left ventricle dilation and excessive inflammatory reactions in the infarcted heart …

An endoscopically compatible fast-gelation powder forms Janus-adhesive hydrogel barrier to prevent postoperative adhesions

Y Jia, J Feng, Z Feng, J Liu, Y Yang… - Proceedings of the …, 2023 - National Acad Sciences
Postoperative adhesions occur widely in various tissues, bringing the risk of secondary
surgery and increased medical burden. Hydrogel barriers with Janus-adhesive ability can …