A conductive and adhesive hydrogel composed of MXene nanoflakes as a paintable cardiac patch for infarcted heart repair

M Lee, J Park, G Choe, S Lee, BG Kang, JH Jun… - ACS …, 2023 - ACS Publications
Myocardial infarction (MI) is a major cause of death worldwide. After the occurrence of MI,
the heart frequently undergoes serious pathological remodeling, leading to excessive …

L‐Arginine‐Loaded gold nanocages ameliorate myocardial ischemia/reperfusion injury by promoting nitric oxide production and maintaining mitochondrial function

Z Wang, N Yang, Y Hou, Y Li, C Yin, E Yang… - Advanced …, 2023 - Wiley Online Library
Cardiovascular disease is the leading cause of death worldwide. Reperfusion therapy is
vital to patient survival after a heart attack but can cause myocardial ischemia/reperfusion …

Multifunctional elastomer cardiac patches for preventing left ventricle remodeling after myocardial infarction in vivo

Y Yao, A Li, S Wang, Y Lu, J Xie, H Zhang, D Zhang… - Biomaterials, 2022 - Elsevier
Myocardial infarction (MI) is still a major cause of mortality and morbidity worldwide.
Elastomer cardiac patches have shown great potential in preventing left ventricle (LV) …

Can't handle the stress? Mechanobiology and disease

N Zuela-Sopilniak, J Lammerding - Trends in molecular medicine, 2022 - cell.com
Mechanobiology is a rapidly growing research area focused on how mechanical forces and
properties influence biological systems at the cell, molecular, and tissue level, and how …

A Matrix‐Metalloproteinase‐Responsive Hydrogel System for Modulating the Immune Microenvironment in Myocardial Infarction

W Chen, C Wang, W Liu, B Zhao, Z Zeng… - Advanced …, 2023 - Wiley Online Library
Injectable hydrogels carrying therapeutic factors to modulate the infarct immune
microenvironment show great potential in the treatment of myocardial infarction (MI) …

ROS-responsive polyurethane fibrous patches loaded with methylprednisolone (MP) for restoring structures and functions of infarcted myocardium in vivo

Y Yao, J Ding, Z Wang, H Zhang, J Xie, Y Wang… - Biomaterials, 2020 - Elsevier
Reactive oxygen species (ROS) play an important role in the pathogenesis of numerous
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …

Black bioceramics: combining regeneration with therapy

X Wang, J Xue, B Ma, JF Wu, J Chang… - Advanced …, 2020 - Wiley Online Library
Bioceramics have been developed from bioinert to bioactive or biodegradable materials in
the past few decades. However, at present, traditional bioceramics are still mainly used in …

Biomedical engineering of polysaccharide-based tissue adhesives: Recent advances and future direction

H Shokrani, A Shokrani, F Seidi, MT Munir… - Carbohydrate …, 2022 - Elsevier
Tissue adhesives have been widely used for preventing wound leaks, sever bleeding, as
well as for enhancing drug delivery and biosensing. However, only a few among suggested …

Recent development in therapeutic cardiac patches

X Mei, K Cheng - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
For the past decades, heart diseases remain the leading cause of death worldwide. In the
adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic …

Alleviating oxidative injury of myocardial infarction by a fibrous polyurethane patch with condensed ROS‐scavenging backbone units

J Xie, Y Yao, S Wang, L Fan, J Ding… - Advanced …, 2022 - Wiley Online Library
Excessive reactive oxygen species (ROS) generated after myocardial infarction (MI) result in
the oxidative injury in myocardium. Implantation of antioxidant biomaterials, without the use …