The chemokine receptors CXCR1/2 and their ligand CXCL8 are essential for the activation
and trafficking of inflammatory mediators as well as tumor progression and metastasis. The …

Hepatocellular carcinoma (HCC) is the most common primary liver tumor and the third
greatest cause of cancer-related death worldwide, and its incidence is increasing. Despite …

Hepatocellular carcinoma (HCC) is one of the most common and aggressive human cancers
worldwide. HCC is an example of inflammation‐related cancer and represents a paradigm …

Problem Endometriosis is a chronic inflammatory disease associated with an impairment in
immune response. Disorders in the peritoneal fluid and ectopic endometrium macrophage …

Cancers harbor significant genetic heterogeneity and patterns of relapse following many
therapies are due to evolved resistance to treatment. While efforts have been made to …

It is well established that chronic inflammation underpins the development of a number of
human cancers, with pro-inflammatory signaling within the tumor microenvironment …

Epidermal growth factor (EGF) and their receptor (EGFR) play an important role in the
development of cancer proliferation, and metastasis, although the mechanism remains …

Background & aims Inflammation is a hallmark of cancer, yet the mechanisms that regulate
immune cell infiltration into tumors remain poorly characterized. This study attempted to …

The CCR3 gene plays a critical role in allergic airway inflammation, such as allergic rhinitis
(AR), and there is an inflammatory signal link between the nasal cavity and the CCR3 gene …

Background It is well documented that cancer cells secrete angiogenic factors to recruit and
sustain tumor vascular networks. However, little is known about the effects of endothelial …