Critical review of the evolution of extracellular vesicles' knowledge: from 1946 to today

E Bazzan, M Tinè, A Casara, D Biondini… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are a family of particles/vesicles present in blood and body
fluids, composed of phospholipid bilayers that carry a variety of molecules that can mediate …

Applications of charge detection mass spectrometry in molecular biology and biotechnology

MF Jarrold - Chemical reviews, 2021 - ACS Publications
Charge detection mass spectrometry (CDMS) is a single-particle technique where the
masses of individual ions are determined from simultaneous measurement of their mass-to …

Prospective therapeutic applications of platelet extracellular vesicles

J Johnson, YW Wu, C Blyth, G Lichtfuss… - Trends in …, 2021 - cell.com
There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for
regenerative medicine and drug delivery. Blood-borne platelets represent a source of …

Expanding applications of allogeneic platelets, platelet lysates, and platelet extracellular vesicles in cell therapy, regenerative medicine, and targeted drug delivery

T Burnouf, ML Chou, DJ Lundy, EY Chuang… - Journal of Biomedical …, 2023 - Springer
Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

How C-reactive protein structural isoforms with distinctive bioactivities affect disease progression

IM Rajab, PC Hart, LA Potempa - Frontiers in immunology, 2020 - frontiersin.org
C-reactive protein (CRP) is a widely known, hepatically synthesized protein whose blood
levels change rapidly and pronouncedly in response to any tissue damaging event …

Exosomes as emerging drug delivery and diagnostic modality for breast cancer: recent advances in isolation and application

DN Kumar, A Chaudhuri, F Aqil, D Dehari, R Munagala… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is considered the second most occurring cancer after lung
cancer globally. The treatment for breast cancer includes surgery, radiation, chemotherapy …

Platelets at the crossroads of pro-inflammatory and resolution pathways during inflammation

N Ludwig, A Hilger, A Zarbock, J Rossaint - Cells, 2022 - mdpi.com
Platelets are among the most abundant cells in the mammalian circulation. Classical platelet
functions in hemostasis and wound healing have been intensively explored and are …

Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules

G Marcoux, A Laroche, S Hasse… - Blood, The Journal …, 2021 - ashpublications.org
In addition to their hemostatic role, platelets play a significant role in immunity. Once
activated, platelets release extracellular vesicles (EVs) formed by the budding of their …

Extracellular vesicles: new players in regulating vascular barrier function

V Chatterjee, X Yang, Y Ma, MH Wu… - American Journal of …, 2020 - journals.physiology.org
Extracellular vesicles (EVs) have attracted rising interests in the cardiovascular field not only
because they serve as serological markers for circulatory disorders but also because they …

[HTML][HTML] A novel role for necroptosis in the pathogenesis of necrotizing enterocolitis

AD Werts, WB Fulton, MR Ladd, A Saad-Eldin… - Cellular and molecular …, 2020 - Elsevier
Background & Aims Necrotizing enterocolitis (NEC) is a devastating disease of premature
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and …