Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

Breast cancer: current perspectives on the disease status

M Fahad Ullah - Breast cancer metastasis and drug resistance …, 2019 - Springer
Breast cancer is the most frequently diagnosed cancer in women and ranks second among
causes for cancer related death in women. Evidence in literature has shown that the past …

Nanotechnology for multimodal synergistic cancer therapy

W Fan, B Yung, P Huang, X Chen - Chemical reviews, 2017 - ACS Publications
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Stimuli‐responsive NO release for on‐demand gas‐sensitized synergistic cancer therapy

W Fan, BC Yung, X Chen - Angewandte Chemie International …, 2018 - Wiley Online Library
Featuring high biocompatibility, the emerging field of gas therapy has attracted extensive
attention in the medical and scientific communities. Currently, considerable research has …

Mechanisms and insights into drug resistance in cancer

H Zahreddine, KLB Borden - Frontiers in pharmacology, 2013 - frontiersin.org
Cancer drug resistance continues to be a major impediment in medical oncology. Clinically,
resistance can arise prior to or as a result of cancer therapy. In this review, we discuss …

Natural products for the management and prevention of breast cancer

S Mitra, R Dash - Evidence‐Based Complementary and …, 2018 - Wiley Online Library
Among all types of cancer, breast cancer is one of the most challenging diseases, which is
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …

Therapy resistance mediated by exosomes

TB Steinbichler, J Dudás, S Skvortsov, U Ganswindt… - Molecular cancer, 2019 - Springer
Therapy resistance can arise within tumor cells because of genetic or phenotypic changes
(intrinsic resistance), or it can be the result of an interaction with the tumor microenvironment …

Understanding cancer and the anticancer activities of naphthoquinones–a review

KW Wellington - RSC advances, 2015 - pubs.rsc.org
The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

Three decades of P-gp inhibitors: skimming through several generations and scaffolds

A Palmeira, E Sousa, MH Vasconcelos… - Current medicinal …, 2012 - ingentaconnect.com
Many tumor cells become resistant to commonly used cytotoxic drugs due to the
overexpression of ATP-binding cassette (ABC) transporters, namely P-glycoprotein (P-gp) …