[HTML][HTML] The emerging roles of the adaptive immune response in acute pancreatitis

B Stojanovic, IP Jovanovic, MD Stojanovic… - Cells, 2023 - mdpi.com
Acute pancreatitis (AP) is an abrupt, variable inflammatory condition of the pancreas,
potentially escalating to severe systemic inflammation, rampant pancreatic necrosis, and …

IL-17 in type II diabetes mellitus (T2DM) immunopathogenesis and complications; molecular approaches

R Elahi, M Nazari, V Mohammadi, K Esmaeilzadeh… - Molecular …, 2024 - Elsevier
Chronic inflammation has long been considered the characteristic feature of type II diabetes
mellitus (T2DM) Immunopathogenesis. Pro-inflammatory cytokines are considered the …

[HTML][HTML] Gut microbiota aggravates neutrophil extracellular traps-induced pancreatic injury in hypertriglyceridemic pancreatitis

G Li, L Liu, T Lu, Y Sui, C Zhang, Y Wang… - Nature …, 2023 - nature.com
Hypertriglyceridemic pancreatitis (HTGP) is featured by higher incidence of complications
and poor clinical outcomes. Gut microbiota dysbiosis is associated with pancreatic injury in …

[HTML][HTML] B Cells and Double-Negative B Cells (CD27IgD) Are Related to Acute Pancreatitis Severity

F Malheiro, M Ângelo-Dias, T Lopes, S Azeredo-Lopes… - Diseases, 2024 - mdpi.com
Acute pancreatitis (AP) is an increasingly frequent disease in which inflammation plays a
crucial role. Fifty patients hospitalized with AP were included and peripheral blood samples …

[HTML][HTML] USP25 Deficiency Exacerbates Acute Pancreatitis via Up-Regulating TBK1–NF-κB Signaling in Macrophages

X Liu, W Luo, J Chen, C Hu, RN Mutsinze… - Cellular and Molecular …, 2022 - Elsevier
Background & Aims Severe acute pancreatitis can easily lead to systemic inflammatory
response syndrome and death. Macrophages are known to be involved in the …

[HTML][HTML] The combination of four main components in Xuebijing injection improved the preventive effects of Cyclosporin A in acute graft-versus-host disease mice by …

T Shang, Y Guo, XR Li, Z Zhou, Y Qi, K Salahdiin… - Biomedicine & …, 2022 - Elsevier
Acute graft-versus-host disease (aGVHD) is a major life-threatening complication after
Allogeneic Hematopoietic Stem Cell Transplant (allo-HSCT). Although a series of …

[HTML][HTML] The role of mitochondrial damage-associated molecular patterns in acute pancreatitis

Y Zhou, X Huang, Y Jin, M Qiu, PC Ambe… - Biomedicine & …, 2024 - Elsevier
Acute pancreatitis (AP) is one of the most common gastrointestinal tract diseases with
significant morbidity and mortality. Current treatments remain unspecific and supportive due …

[HTML][HTML] IL27 and IL1RN are causally associated with acute pancreatitis: a Mendelian randomization study

Q Jing, X Liu, Z Lv, D Xue - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: The interleukin (IL) plays a role in the development of acute pancreatitis (AP).
However, the specific IL in AP has not been fully revealed. Therefore, the association …

Sitagliptin ameliorates L-arginine-induced acute pancreatitis via modulating inflammatory cytokines expression and combating oxidative stress

HM Eltahir, HM Elbadawy, MA Almikhlafi… - Frontiers in …, 2024 - frontiersin.org
Background Acute pancreatitis (AP) is an inflammatory condition that resolves
spontaneously, but occasionally, develops into systemic inflammation, organ failure and …

[HTML][HTML] Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR

Y Huangfu, X Yu, C Wan, Y Zhu, Z Wei, F Li… - Frontiers in …, 2023 - frontiersin.org
Severe acute pancreatitis (SAP) is a lethal gastrointestinal disorder, yet no specific and
effective treatment is available. Its pathogenesis involves inflammatory cascade, oxidative …