Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …

Simple Summary Prostate cancer can develop under hormone treatment and chemotherapy
from a castration-sensitive towards a castration-resistant into a drug resistant-tumor. The …

Despite aggressive treatment for localized cancer, prostate cancer (PC) remains a leading
cause of cancer-related death for American men due to a subset of patients progressing to …

Prostate cancer is the most common malignancy and the second leading cause of cancer-
related deaths in men. One common treatment is androgen-deprivation therapy, which …

New chemical inhibitors of protein–protein interactions are needed to propel advances in
molecular pharmacology. Peptoids are peptidomimetic oligomers with the capability to …

Simple Summary Castration-resistant prostate cancer (CRPC) remains a significant medical
challenge, even with recent advancements in diagnosis and treatment. To improve patient …

The androgen receptor is a transcription factor and validated therapeutic target for prostate
cancer. Androgen deprivation therapy remains the gold standard treatment, but it is not …

Prostate cancer is the second leading cause of cancer-related deaths among men in North
America. Almost all prostate cancers begin in an androgen-dependent state, so androgen …

Prostate cancer has become a real public health issue in industrialized countries, mainly
due to patients' relapse by castration-refractory disease after androgen ablation. Castration …

Prostate cancer is the second leading cause of cancer related death in American men.
Androgen deprivation therapy (ADT) is used to treat patients with aggressive prostate …