Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer

Y Liu, Y Shi, R Han, C Liu, X Qin, P Li, R Gu - Frontiers in immunology, 2023 - frontiersin.org
Gastric cancer is one of the top causes of cancer-related death globally. Although novel
treatment strategies have been developed, attempts to eradicate gastric cancer have been …

Long non‐coding RNA PVT1: Emerging biomarker in digestive system cancer

DD Zhou, X Liu, C Lu, OP Pant, X Liu - Cell proliferation, 2017 - Wiley Online Library
The digestive system cancers are leading cause of cancer‐related death worldwide, and
have high risks of morbidity and mortality. More and more long non‐coding RNA s (lnc RNA …

Identification of potential key genes associated with the pathogenesis and prognosis of gastric cancer based on integrated bioinformatics analysis

X Liu, J Wu, D Zhang, Z Bing, J Tian, M Ni… - Frontiers in …, 2018 - frontiersin.org
Background and Objective: Despite striking advances in multimodality management, gastric
cancer (GC) remains the third cause of cancer mortality globally and identifying novel …

The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancer

T Huang, HW Liu, JQ Chen, SH Wang, LQ Hao… - Biomedicine & …, 2017 - Elsevier
Background Recent evidence has highlighted the key regulatory roles of long non-coding
RNAs (lncRNAs) in tumor development and progression including gastric cancer (GC). The …

[HTML][HTML] Zinc finger protein 384 enhances colorectal cancer metastasis by upregulating MMP2

Z Yan, Y Zhou, Y Yang, C Zeng, P Li… - Oncology …, 2022 - spandidos-publications.com
Zinc finger proteins (ZNFs) serve key roles in tumor formation and progression; however, the
functions and underlying mechanisms of dysregulated ZNF384 in colorectal cancer (CRC) …

Targeting HIF-1α signaling pathway for gastric cancer treatment

H Li, Y Jia, Y Wang - Die Pharmazie-An International Journal of …, 2019 - ingentaconnect.com
Gastric cancer is a common malignancy with high mortality and limited therapeutic options.
Hypoxia inducible factor-1 α (HIF-1α) is the key responser adapted to tumor hypoxia. Under …

The prognostic outcome of 'type 2 diabetes mellitus and breast cancer'association pivots on hypoxia-hyperglycemia axis

IA Durrani, A Bhatti, P John - Cancer cell international, 2021 - Springer
Type 2 diabetes mellitus and breast cancer are complex, chronic, heterogeneous, and multi-
factorial diseases; with common risk factors including but not limited to diet, obesity, and …

Proteomics and Metabolomics Unveil Codonopsis pilosula (Franch.) Nannf. Ameliorates Gastric Precancerous Lesions via Regulating Energy Metabolism

R He, R Ma, Z Jin, Y Zhu, F Yang, F Hu… - Frontiers in …, 2022 - frontiersin.org
Objective: This study aimed to systematically evaluate the efficacy of Codonopsis pilosula
(Franch.) Nannf.(Codonopsis Radix, CR) and reveal the mechanism of its effects on …

[HTML][HTML] Functionally enhanced cell spheroids for stem cell therapy: Role of TIMP1 in the survival and therapeutic effectiveness of stem cell spheroids

JK Choi, H Chung, SJ Oh, JW Kim, SH Kim - Acta Biomaterialia, 2023 - Elsevier
Stem cell therapy has emerged as a promising regenerative medicine strategy but is limited
by poor cell survival, leading to low therapeutic outcomes. We developed cell spheroid …

Global transcriptomic analysis suggests carbon dioxide as an environmental stressor in spaceflight: A systems biology GeneLab case study

A Beheshti, E Cekanaviciute, DJ Smith, SV Costes - Scientific reports, 2018 - nature.com
Spaceflight introduces a combination of environmental stressors, including microgravity,
ionizing radiation, changes in diet and altered atmospheric gas composition. In order to …