Long-term depression (LTD) in the CNS has been the subject of intense investigation as a
process that may be involved in learning and memory and in various pathological …

Mechanisms of local damage Mechanisms of “distant” damage Relevance to human
epilepsy Clinical considerations Relevance of animal models for human temporal lobe …

N-methyl-d-aspartate receptors (NMDARs) are known for their role in the induction of long-
term potentiation (LTP). Here we start by reviewing the early evidence for their role in LTP at …

Storage and processing of information at the synaptic level is enabled by the ability of
synapses to persistently alter their efficacy. This phenomenon, known as synaptic plasticity …

On the occasion of the 40 year anniversary of the hugely impactful review by Richard (Dick)
Evans and Jeff Watkins, we describe how their work has impacted the field of synaptic …

The excitatory responses to l-glutamate (l-Glu), quisqualate (QA) and kainate (KA) have
been investigated in isolated pyramidal cells from rat hippocampus using intracellular …

Kainate receptor-mediated presynaptic inhibition at the mouse hippocampal mossy fibre
synapse - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

1. The action of a short bath application of kainic acid (KA, 200‐250 nM, 3‐5 min) on the
CA3 region of rat hippocampal slices has been studied with intracellular and extracellular …

Cyano-2, 3-dihydroxy-7-nitro-quinoxaline (CNQX; FG 9065) is a new excitatory amino acid
antagonist. In the spinal cord it has been reported to selectively block responses to acidic …

Different types of memory are thought to rely on different types of synaptic plasticity, many of
which depend on the activation of the N-Methyl-D Aspartate (NMDA) subtype of glutamate …