Diversity of cells and signals in the cardiovascular system

E Grandi, MF Navedo, JJ Saucerman… - The Journal of …, 2023 - Wiley Online Library
This white paper is the outcome of the seventh UC Davis Cardiovascular Research
Symposium on Systems Approach to Understanding Cardiovascular Disease and …

Depression and atrial fibrillation in a reciprocal liaison: a neuro-cardiac link

TA Manolis, AA Manolis… - … Journal of Psychiatry …, 2023 - Taylor & Francis
Objective To explore the reciprocal relationship of depression and atrial fibrillation (AF).
Methods A literature search was conducted in Pub Med, Scopus, and Google Scholar using …

Cytotoxic CD8+ T Cells Are Involved in the Thrombo-Inflammatory Response during First-Diagnosed Atrial Fibrillation

J Friebel, M Witkowski, M Wegner, L Blöbaum… - Cells, 2022 - mdpi.com
Background: Atrial myopathy and atrial fibrillation (AF) accompany thrombo-inflammation.
This facilitates disease progression and promotes major adverse cardiovascular events …

Markers of atrial myopathy in the general population: prevalence, predictors, and inter-relations

LS Johnson, PG Platonov, D Conen, C Kennbäck… - Clinical …, 2023 - jacc.org
Background Atrial myopathy refers to structural and functional cardiac abnormalities
associated with atrial fibrillation and stroke, but appropriate diagnostic criteria are lacking …

[HTML][HTML] Gut microbiota and atrial fibrillation: pathogenesis, mechanisms and therapies

AM Al-Kaisey, W Figgett, J Hawson… - Arrhythmia & …, 2023 - ncbi.nlm.nih.gov
Over the past decade there has been an interest in understanding the role of gut microbiota
in the pathogenesis of AF. A number of studies have linked the gut microbiota to the …

Pathophysiology and clinical relevance of atrial myopathy

MRL Tubeeckx, GW De Keulenaer… - Basic Research in …, 2024 - Springer
Atrial myopathy is a condition that consists of electrical, structural, contractile, and autonomic
remodeling of the atria and is the substrate for development of atrial fibrillation, the most …

In silico analysis of the dynamic regulation of cardiac electrophysiology by Kv11.1 ion‐channel trafficking

S Meier, A Grundland, D Dobrev… - The Journal of …, 2023 - Wiley Online Library
Cardiac electrophysiology is regulated by continuous trafficking and internalization of ion
channels occurring over minutes to hours. Kv11. 1 (also known as hERG) underlies the …

Mechanisms and effects of metformin on skeletal muscle disorders

R Shang, J Miao - Frontiers in Neurology, 2023 - frontiersin.org
Skeletal muscle disorders are mostly genetic and include several rare diseases. With
disease progression, muscle fibrosis and adiposis occur, resulting in limited mobility. The …

Janus Nanofibrous Patch with In Situ Grown Superlubricated Skin for Soft Tissue Repair with Inhibited Postoperative Adhesion

Q Wang, J Du, J Meng, J Yang, Y Cao, J Xiang, J Yu… - ACS …, 2024 - ACS Publications
The patch with a superlubricated surface shows great potential for the prevention of
postoperative adhesion during soft tissue repair. However, the existing patches suffer from …

Targeting the Substrate for Atrial Fibrillation: JACC Review Topic of the Week

MD McCauley, G Iacobellis, N Li, S Nattel… - Journal of the American …, 2024 - jacc.org
The identification of the pulmonary veins as a trigger source for atrial fibrillation (AF) has
established pulmonary vein isolation (PVI) as a key target for AF ablation. However, PVI …