Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …

Background Osteoarthritis (OA) is the most common chronic disease. It is characterized by
high levels of clinical heterogeneity and low inflammation. Therefore, elucidation of the …

Ethnopharmacological relevance Euphorbium is the resinous secretion of Euphorbia
resinifera Berg. According to the record, Euphorbium was first used by Roman doctors to …

The recent pandemic we are experiencing caused by the coronavirus disease 2019 (COVID-
19) has put the world's population on the rack, with more than 191 million cases and more …

Sarcoidosis embodies a complex inflammatory disorder spanning multiple systems, with its
origin remaining elusive. It manifests as the infiltration of inflammatory cells that coalesce …

Background: Gouty arthritis (GA) is a common inflammatory disease that causes pain due to
the deposition of monosodium urate (MSU) crystals into joints and surrounding tissues. Anti …

Eleutheroside E, a major natural bioactive compound in Acanthopanax senticosus (Rupr.
etMaxim.) Harms, possesses anti-oxidative, anti-fatigue, anti-inflammatory, anti-bacterial and …

Abstract Three novel lignans (1, 5 and 6) and two novel quinic acids (16 and 17) along with
15 known phenylpropanoids were obtained from the ethanol extract of Zanthoxylum nitidum …

Caspase-1 is a critical mediator of the inflammatory process by activating various pro-
inflammatory cytokines such as pro-IL-1β, IL-18 and IL-33. Uncontrolled activation of …