Acute coronary syndromes
BA Bergmark, N Mathenge, PA Merlini… - The Lancet, 2022 - thelancet.com
Although substantial progress has been made in the diagnosis and treatment of acute
coronary syndromes, cardiovascular disease remains the leading cause of death globally …
coronary syndromes, cardiovascular disease remains the leading cause of death globally …
[HTML][HTML] The role of inflammation in cardiovascular disease
MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …
prominent role in its development and progression. Inflammation-induced endothelial …
Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities
LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
Targeting the NLRP3 inflammasome in cardiovascular diseases
The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …
Colchicine in cardiovascular disease: in-depth review
SG Deftereos, FJ Beerkens, B Shah, G Giannopoulos… - Circulation, 2022 - Am Heart Assoc
Inflammation plays a prominent role in the development of atherosclerosis and other
cardiovascular diseases, and anti-inflammatory agents may improve cardiovascular …
cardiovascular diseases, and anti-inflammatory agents may improve cardiovascular …
Macrophages in cardiac remodelling after myocardial infarction
J Yap, J Irei, J Lozano-Gerona, S Vanapruks… - Nature Reviews …, 2023 - nature.com
Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …
Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials
ATL Fiolet, TSJ Opstal, A Mosterd… - European Heart …, 2021 - academic.oup.com
Aims Recent randomized trials demonstrated a benefit of low-dose colchicine added to
guideline-based treatment in patients with recent myocardial infarction or chronic coronary …
guideline-based treatment in patients with recent myocardial infarction or chronic coronary …
Colchicine and the heart
M Imazio, M Nidorf - European Heart Journal, 2021 - academic.oup.com
Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for
decades for the prevention of acute inflammatory flares in gout and familial Mediterranean …
decades for the prevention of acute inflammatory flares in gout and familial Mediterranean …
The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases
An intense, stereotyped inflammatory response occurs in response to ischaemic and non-
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …
Effect of colchicine on myocardial injury in acute myocardial infarction
N Mewton, F Roubille, D Bresson, C Prieur, C Bouleti… - Circulation, 2021 - Am Heart Assoc
Background: Inflammation is a key factor of myocardial damage in reperfused ST-segment–
elevation myocardial infarction. We hypothesized that colchicine, a potent anti-inflammatory …
elevation myocardial infarction. We hypothesized that colchicine, a potent anti-inflammatory …