[HTML][HTML] Evaluating the promise of inclusion of African ancestry populations in genomics
AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …
known, and the resultant scientific and ethical limitations are becoming increasingly …
[HTML][HTML] Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases
J Alvar, F Alves, B Bucheton, L Burrows… - Seminars in …, 2020 - Springer
Progress has been made in the control or elimination of tropical diseases, with a significant
reduction of incidence. However, there is a risk of re-emergence if the factors fueling …
reduction of incidence. However, there is a risk of re-emergence if the factors fueling …
Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors
DA Rocha, EB Silva, IS Fortes, MS Lopes… - European Journal of …, 2018 - Elsevier
Abstract Chagas disease and Human African trypanosomiasis (HAT) are important public
health issues in Latin American and sub-Saharan African countries, respectively, and are …
health issues in Latin American and sub-Saharan African countries, respectively, and are …
The role of HLA‐G in parasitic diseases
Little attention has been devoted to the role of HLA‐G gene and molecule on parasitic
disorders, and the available studies have focused on malaria, African and American …
disorders, and the available studies have focused on malaria, African and American …
[HTML][HTML] Immunomodulatory Potential of Non-Classical HLA-G in Infections including COVID-19 and Parasitic Diseases
S Rashidi, C Vieira, R Tuteja, R Mansouri… - Biomolecules, 2022 - mdpi.com
Human Leukocyte Antigen-G (HLA-G), a polymorphic non-classical HLA (HLA-Ib) with
immune-regulatory properties in cancers and infectious diseases, presents both membrane …
immune-regulatory properties in cancers and infectious diseases, presents both membrane …
[PDF][PDF] The H3Africa Consortium: publication outputs of a pan-African genomics collaboration (2013 to 2020)
Developing a complex collaborative program across multiple African countries,
characterized by a diversity of government models, laws, cultures and norms, resources and …
characterized by a diversity of government models, laws, cultures and norms, resources and …
[HTML][HTML] No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations
Background Human African trypanosomiasis (HAT) manifests as an acute form caused by
Trypanosoma brucei rhodesiense (Tbr) and a chronic form caused by Trypanosoma brucei …
Trypanosoma brucei rhodesiense (Tbr) and a chronic form caused by Trypanosoma brucei …
[HTML][HTML] DIA-based technology explores hub pathways and biomarkers of neurological recovery in ischemic stroke after rehabilitation
W Hu, P Li, N Zeng, S Tan - Frontiers in Neurology, 2023 - frontiersin.org
Objective Ischemic stroke (IS) is a common disease that causes severe and long-term
neurological disability in people worldwide. Although rehabilitation is indispensable to …
neurological disability in people worldwide. Although rehabilitation is indispensable to …
Inflammation following trypanosome infection and persistence in the skin
D Mabille, G Caljon - Current Opinion in Immunology, 2020 - Elsevier
Highlights•The skin is transformed from an initial barrier to a reservoir tissue.•Skin-dwelling
trypanosomes sustain transmission and complicate diagnosis.•Trypanosomes modulate and …
trypanosomes sustain transmission and complicate diagnosis.•Trypanosomes modulate and …
[HTML][HTML] Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in …
CN Mutuku, R Bateta, MK Rono, JM Njunge… - International Journal for …, 2021 - Elsevier
Abstract Human African Trypanosomiasis (HAT) is a disease of major economic importance
in Sub-Saharan Africa. The HAT is caused by Trypanosoma brucei rhodesiense (Tbr) …
in Sub-Saharan Africa. The HAT is caused by Trypanosoma brucei rhodesiense (Tbr) …