[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank

LT Elliott, K Sharp, F Alfaro-Almagro, S Shi, KL Miller… - Nature, 2018 - nature.com
The genetic architecture of brain structure and function is largely unknown. To investigate
this, we carried out genome-wide association studies of 3,144 functional and structural brain …

Quantitative assessment of structural image quality

AFG Rosen, DR Roalf, K Ruparel, J Blake, K Seelaus… - Neuroimage, 2018 - Elsevier
Data quality is increasingly recognized as one of the most important confounding factors in
brain imaging research. It is particularly important for studies of brain development, where …

Enhancing the informativeness and replicability of imaging genomics studies

CS Carter, CE Bearden, ET Bullmore, DH Geschwind… - Biological …, 2017 - Elsevier
Imaging genomics is a new field of investigation that seeks to gain insights into the impact of
human genetic variation on the structure, chemistry, and function of neural systems in health …

A meta‐analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the …

BA Gutman, TGM Van Erp, K Alpert… - Human brain …, 2022 - Wiley Online Library
Schizophrenia is associated with widespread alterations in subcortical brain structure. While
analytic methods have enabled more detailed morphometric characterization, findings are …

Structural brain abnormalities in youth with psychosis spectrum symptoms

TD Satterthwaite, DH Wolf, ME Calkins… - JAMA …, 2016 - jamanetwork.com
Importance Structural brain abnormalities are prominent in psychotic disorders, including
schizophrenia. However, it is unclear when aberrations emerge in the disease process and …

[HTML][HTML] Heritability and reliability of automatically segmented human hippocampal formation subregions

CD Whelan, DP Hibar, LS Van Velzen, AS Zannas… - Neuroimage, 2016 - Elsevier
The human hippocampal formation can be divided into a set of cytoarchitecturally and
functionally distinct subregions, involved in different aspects of memory formation …

Glutamate imaging (GluCEST) reveals lower brain GluCEST contrast in patients on the psychosis spectrum

DR Roalf, RPR Nanga, PE Rupert, H Hariharan… - Molecular …, 2017 - nature.com
Psychosis commonly develops in adolescence or early adulthood. Youths at clinical high
risk (CHR) for psychosis exhibit similar, subtle symptoms to those with schizophrenia (SZ) …

[HTML][HTML] The genetic architecture of human amygdala volumes and their overlap with common brain disorders

YN Ou, BS Wu, YJ Ge, Y Zhang, YC Jiang… - Translational …, 2023 - nature.com
The amygdala is a crucial interconnecting structure in the brain that performs several
regulatory functions, yet its genetic architectures and involvement in brain disorders remain …

[HTML][HTML] Multidimensional heritability analysis of neuroanatomical shape

T Ge, M Reuter, AM Winkler, AJ Holmes, PH Lee… - Nature …, 2016 - nature.com
In the dawning era of large-scale biomedical data, multidimensional phenotype vectors will
play an increasing role in examining the genetic underpinnings of brain features, behaviour …

[HTML][HTML] Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort

S Grama, I Willcocks, JJ Hubert, AF Pardiñas… - Translational …, 2020 - nature.com
Research has shown differences in subcortical brain volumes between participants with
schizophrenia and healthy controls. However, none of these differences have been found to …