Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are
specialized to detect and transduce diverse environmental stimuli to the central nervous …

Following colonic inflammation, the uninjured bladder afferent neurons are also activated.
The mechanisms and pathways underlying this sensory neuron cross-activation (from …

Non-neuronal cells constitute 90%–95% of sensory ganglia. These cells, especially glial
and immune cells, play critical roles in the modulation of sensory neurons. This study aimed …

We report that diazepam binding inhibitor (DBI) is a glial messenger mediating satellite glia-
sensory neuron crosstalk in the dorsal root ganglion (DRG). DBI is highly expressed in …

Neuropathic pain is a highly prevalent and refractory condition, yet its mechanism remains
poorly understood. While NR1, the essential subunit of NMDA receptors, has long been …

Background: Recent studies have shown that peripheral nerve regeneration process is
closely related to neuropathic pain. Toll-like receptor 4 (TLR4) signaling was involved in …

Satellite glial cells (SGCs) are a type of glial cell population that originates from neural crest
cells. They ultimately migrate to surround the cell bodies of neurons in the ganglia of the …

Monoamine-targeting antidepressants serve as frontline medications for chronic pain and
associated comorbidities. While persistent anti-allodynic properties of antidepressants …

Head and neck squamous cell carcinoma (HNSCC) is painful, and perineural invasion (PNI)
has been associated with the worst pain. Pain due to HNSCC is diverse and may vary based …

We report that diazepam binding inhibitor (DBI) is a glial messenger mediating satellite glia-
sensory neuron crosstalk in the dorsal root ganglion (DRG). DBI is highly and specifically …