Towards an integrated model of bacterial conjugation

E Cabezón, J Ripoll-Rozada, A Peña… - FEMS microbiology …, 2015 - academic.oup.com
Bacterial conjugation is one of the main mechanisms for horizontal gene transfer. It
constitutes a key element in the dissemination of antibiotic resistance and virulence genes to …

The diversity of conjugative relaxases and its application in plasmid classification

MP Garcillán-Barcia, MV Francia… - FEMS microbiology …, 2009 - academic.oup.com
Bacterial conjugation is an efficient and sophisticated mechanism of DNA transfer among
bacteria. While mobilizable plasmids only encode a minimal MOB machinery that allows …

Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids

C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

From conjugation to T4S systems in Gram‐negative bacteria: a mechanistic biology perspective

G Waksman - EMBO reports, 2019 - embopress.org
Conjugation is the process by which bacteria exchange genetic materials in a unidirectional
manner from a donor cell to a recipient cell. The discovery of conjugation signalled the dawn …

Breaking and joining single-stranded DNA: the HUH endonuclease superfamily

M Chandler, F De La Cruz, F Dyda… - Nature Reviews …, 2013 - nature.com
HUH endonucleases are numerous and widespread in all three domains of life. The major
function of these enzymes is processing a range of mobile genetic elements by catalysing …

Conjugative DNA metabolism in Gram-negative bacteria

F De La Cruz, LS Frost, RJ Meyer… - FEMS microbiology …, 2010 - academic.oup.com
Bacterial conjugation in Gram-negative bacteria is triggered by a signal that connects the
relaxosome to the coupling protein (T4CP) and transferosome, a type IV secretion system …

Folded DNA in action: hairpin formation and biological functions in prokaryotes

D Bikard, C Loot, Z Baharoglu… - … and Molecular Biology …, 2010 - Am Soc Microbiol
Structured forms of DNA with intrastrand pairing are generated in several cellular processes
and are involved in biological functions. These structures may arise on single-stranded DNA …

Replication and conjugative mobilization of broad host-range IncQ plasmids

R Meyer - Plasmid, 2009 - Elsevier
The IncQ plasmids have a broader host-range than any other known replicating element in
bacteria. Studies on the replication and conjugative mobilization of these plasmids, which …

[HTML][HTML] The winding journey of conjugative plasmids toward a novel host cell

N Fraikin, A Couturier, C Lesterlin - Current Opinion in Microbiology, 2024 - Elsevier
Highlights•Plasmid colonization of a new host requires a predetermined sequence of
events.•Colonization steps are contact initiation, invasion, establishment and …

The different faces of rolling-circle replication and its multifunctional initiator proteins

P Wawrzyniak, G Płucienniczak, D Bartosik - Frontiers in Microbiology, 2017 - frontiersin.org
Horizontal gene transfer (HGT) contributes greatly to the plasticity and evolution of
prokaryotic and eukaryotic genomes. The main carriers of foreign DNA in HGT are mobile …