Glucocorticoids (GCs), the adrenal steroids secreted during stress, endanger the
hippocampus, compromising its ability to survive neurological insults. GCs probably do so …

Zinc is necessary for not only brain development but also brain function. Zinc homeostasis in
the brain is tightly regulated by the brain barrier system and is not easily disrupted by dietary …

The adrenal gland releases mineralocorticoids (MCs) and glucocorticoids (GCs) in response
to a variety of stimuli, including stress. Once released, these adrenal steroids mediate a …

Aging in rats is associated with a loss of hippocampal neurons, which may contribute to age‐
related cognitive deficits. Several lines of evidence suggest that stress and glucocorticoids …

Parkinson's disease is a neurodegenerative disease exhibiting the fastest growth in
incidence in recent years. As with most neurodegenerative diseases, the pathophysiology is …

Catamenial epilepsy is a multifaceted neuroendocrine condition in which seizures are
clustered around specific points in the menstrual cycle, most often around perimenstrual or …

Glucocorticoid receptors (GRs) are glucocorticoid-activated transcription factors that
modulate expression of a variety of neuronal genes. Appropriate control of GR expression is …

Glucocorticoids (GCs), the adrenal steroids secreted during stress, are known to affect
diverse processes involving reactive oxygen species, from exacerbation of ischemic …

Increasing evidence suggests that the detrimental effects of glucocorticoid (GC)
hypersecretion occur by activation of the hypothalamic-pituitary-adrenal (HPA) axis in …

The CNS can mount an inflammatory reaction to excitotoxic insults that contributes to the
emerging brain damage. Therefore, anti‐inflammatory drugs should be beneficial in …