Glutamatergic mechanisms are thought to be involved in stress-induced changes of brain
function, especially in the hippocampus. We hypothesized that alterations caused by the …

In the present study, the effect of corticosterone (CORT) on the generation of long-term
potentiation (LTP) and its underlying mechanism involving neurotrophin gene expression in …

As in many humans suffering from lupus erythematosus, the development of systemic
autoimmunity and inflammation in Fas-deficient MRL-lpr mice is accompanied by CNS …

Dietary zinc deficiency elicits abnormal behavior in stressful environment. It is possible that
abnormal corticosterone secretion in zinc deficiency is linked to abnormal behavior. To …

Striking parallels exist between the neurochemical and toxic effects of stress and
methamphetamine. Despite these similarities, no studies have examined how stress may …

Glucocorticoids bind to hippocampal mineralo-(MR) and gluco-(GR) corticoid receptors and,
at high concentrations (eg as seen following treatment with pharmacological doses of …

Both endogenous and exogenous glucocorticoids (GCs) are known to cause apoptosis in a
number of peripheral tissues and in some cases in the CNS. Additionally, GCs can …

Excessive ethanol (EtOH) use leads to impaired memory and cognition. Using a rat model of
binge‐like intoxication, we tested whether elevated corticosterone (Cort) levels contribute to …

Glucocorticoids potentiate injury to the rodent hippocampus following a variety of metabolic
insults, including hypoxia/ischemia, both in vitro and in vivo. We have examined whether …

Objective To review the main neuropsychiatric disorders and cognitive deficits in patients
with Cushing's disease (CD) and the associated pathophysiological mechanisms underlying …