Repeated restraint stress alters hippocampal glutamate uptake and release in the rat
FU Fontella, DA Vendite, AS Tabajara… - Neurochemical …, 2004 - Springer
Glutamatergic mechanisms are thought to be involved in stress-induced changes of brain
function, especially in the hippocampus. We hypothesized that alterations caused by the …
function, especially in the hippocampus. We hypothesized that alterations caused by the …
Corticosterone inhibits generation of long-term potentiation in rat hippocampal slice: involvement of brain-derived neurotrophic factor
J Zhou, F Zhang, Y Zhang - Brain research, 2000 - Elsevier
In the present study, the effect of corticosterone (CORT) on the generation of long-term
potentiation (LTP) and its underlying mechanism involving neurotrophin gene expression in …
potentiation (LTP) and its underlying mechanism involving neurotrophin gene expression in …
Neurodegeneration in autoimmune MRL-lpr mice as revealed by Fluoro Jade B staining
DA Ballok, JM Millward, B Sakic - Brain research, 2003 - Elsevier
As in many humans suffering from lupus erythematosus, the development of systemic
autoimmunity and inflammation in Fas-deficient MRL-lpr mice is accompanied by CNS …
autoimmunity and inflammation in Fas-deficient MRL-lpr mice is accompanied by CNS …
Susceptibility to stress in young rats after 2-week zinc deprivation
M Watanabe, H Tamano, T Kikuchi, A Takeda - Neurochemistry …, 2010 - Elsevier
Dietary zinc deficiency elicits abnormal behavior in stressful environment. It is possible that
abnormal corticosterone secretion in zinc deficiency is linked to abnormal behavior. To …
abnormal corticosterone secretion in zinc deficiency is linked to abnormal behavior. To …
Chronic stress enhances methamphetamine‐induced extracellular glutamate and excitotoxicity in the rat striatum
DA Tata, BK Yamamoto - Synapse, 2008 - Wiley Online Library
Striking parallels exist between the neurochemical and toxic effects of stress and
methamphetamine. Despite these similarities, no studies have examined how stress may …
methamphetamine. Despite these similarities, no studies have examined how stress may …
Down-regulation of BDNF mRNA, with no effect on trkB or glucocorticoid receptor mRNAs, in the porcine hippocampus after acute dexamethasone treatment
SV Vellucci, RF Parrott, ML Mimmack - Research in Veterinary Science, 2001 - Elsevier
Glucocorticoids bind to hippocampal mineralo-(MR) and gluco-(GR) corticoid receptors and,
at high concentrations (eg as seen following treatment with pharmacological doses of …
at high concentrations (eg as seen following treatment with pharmacological doses of …
The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis
M Roy, RM Sapolsky - Neuroendocrinology, 2003 - karger.com
Both endogenous and exogenous glucocorticoids (GCs) are known to cause apoptosis in a
number of peripheral tissues and in some cases in the CNS. Additionally, GCs can …
number of peripheral tissues and in some cases in the CNS. Additionally, GCs can …
Binge‐like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is …
A Cippitelli, R Damadzic, C Hamelink… - Addiction …, 2014 - Wiley Online Library
Excessive ethanol (EtOH) use leads to impaired memory and cognition. Using a rat model of
binge‐like intoxication, we tested whether elevated corticosterone (Cort) levels contribute to …
binge‐like intoxication, we tested whether elevated corticosterone (Cort) levels contribute to …
Corticosterone accelerates hypoxia-and cyanide-induced ATP loss in cultured hippocampal astrocytes
GC Tombaugh, RM Sapolsky - Brain research, 1992 - Elsevier
Glucocorticoids potentiate injury to the rodent hippocampus following a variety of metabolic
insults, including hypoxia/ischemia, both in vitro and in vivo. We have examined whether …
insults, including hypoxia/ischemia, both in vitro and in vivo. We have examined whether …
Neuropsychiatric disorders and cognitive dysfunction in patients with Cushing's disease
Y Chen, Y Li, C Xiao, Q Sun - Chinese medical journal, 2013 - journals.lww.com
Objective To review the main neuropsychiatric disorders and cognitive deficits in patients
with Cushing's disease (CD) and the associated pathophysiological mechanisms underlying …
with Cushing's disease (CD) and the associated pathophysiological mechanisms underlying …