Antibodies can completely suppress or enhance the antibody response to their specific
antigen by several hundredfold. Immunoglobulin M (IgM) enhances antibody responses via …

Publisher Summary This chapter discusses the essential features of the antibody with
respect to the interaction of antigen with preformed, cell-bound, antibody-like receptors. The …

Prior to sheep red cells (SRC) mice were given 7S or 19S anti-SRC antibodies or mixtures of
both. All 7S preparations suppressed the immune response. All 19S preparations enhanced …

IgG antibodies can suppress more than 99% of the antibody response against the antigen to
which they bind. This is used clinically to prevent rhesus-negative (Rh−) women from …

Specific IgG, passively administered together with particulate antigen, can completely
prevent induction of antibody responses to this antigen. The ability of IgG to suppress …

Antigens, Lymphoid Cells, and the Immune Response deals with the nature and properties
of antigens and with the functional anatomy and cell physiology of the mammalian lymphoid …

Publisher Summary The number of conflicting reports now exist on antigen-induced
suppression suggests that no single hypothesis can be applied to this phenomenon. It is …

The distribution of immune complexes has been studied in mouse spleen stimulated to
contain many germinal centers (GC's). Horseradish peroxidase (HRP)-anti-HRP complexes …

These early days of June remind me of Kierkegaard's anecdote (1843) about an artist who
was asked to paint a mural of the passage of Moses across the Red Sea. He painted the …

Antigen-antibody complexes affect various types of cells by mechanisms which require the
activity of the Fc portion of the antibody. As examples, one can cite systems involving …