Opinion statement Melanoma has a high propensity to metastasize to the brain which
portends a poorer prognosis. With advanced radiation techniques and targeted therapies …

In recent years, advances in melanoma treatment have renewed patient hope. This
comprehensive review emphasizes the evolving treatment landscape, particularly …

Since the first approval for immune checkpoint inhibitors (ICIs) for the treatment of cutaneous
melanoma more than a decade ago, immunotherapy has completely transformed the …

Background Effective treatment options are limited for patients with advanced melanoma
who have progressed on immune checkpoint inhibitors (ICI) and targeted therapies (TT) …

Background Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment;
however, only a subset of patients with brain metastasis (BM) respond to ICI. Activating …

Levothyroxine is a milestone in the treatment of all causes of hypothyroidism. From 19th
century till today, Levothyroxine experienced a great advancement, from hypodermic …

As the number therapeutic options continue to grow for patients with advanced melanoma,
there is likely to be a continued focus on combination strategies. Defining the optimal …

Melanoma, the deadliest of the common skin cancers, has the highest propensity to
metastasize to the brain among solid tumors. Approximately 11% to 17% of earlystage …

Targeted and immune therapies have changed the paradigm of treatment for patients with
metastatic melanoma. Treatment of patients with symptomatic melanoma brain metastases …

Simple Summary This review discusses the topic of prevention of brain metastases from the
most frequent solid tumor types, ie, lung cancer, breast cancer and melanoma. Within each …