Expression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumour invasion

K Dallaglio, T Petrachi, A Marconi, F Truzzi… - British journal of …, 2014 - nature.com
Background: Survivin is detected in few adult normal cells and it is highly expressed in
cancer. Nuclear survivin facilitates cell cycle entry, whereas the mitochondrial pool protects …

[HTML][HTML] Perlecan expression influences the keratin 15‐positive cell population fate in the epidermis of aging skin

M Dos Santos, A Michopoulou, V André‐Frei… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
The epidermis is continuously renewed by stem cell proliferation and differentiation. Basal
keratinocytes append the dermal‐epidermal junction, a cell surface‐associated …

The exercise cytokine interleukin-15 rescues slow wound healing in aged mice

W Wong, ED Crane, Y Kuo, A Kim, JD Crane - Journal of Biological …, 2019 - ASBMB
Impaired wound healing in elderly individuals increases infection risk and prolongs surgical
recovery, but current treatment options are limited. Low doses of interleukin-15 (IL-15) that …

[HTML][HTML] Vieillissement et intégrité de la peau-De la biologie cutanée aux stratégies anti-âge

J Rorteau, FP Chevalier, B Fromy… - médecine …, 2020 - medecinesciences.org
La peau est un organe sentinelle, soumis au vieillissement chronologique et
environnemental qui fragilise sa structure et ses fonctions. La fonction barrière de la peau …

Epidermal stem cells: skin surveillance and clinical perspective

X Tang, J Wang, J Chen, W Liu, P Qiao, H Quan… - Journal of Translational …, 2024 - Springer
The skin epidermis is continually influenced by a myriad of internal and external elements.
At its basal layer reside epidermal stem cells, which fuels epidermal renovation and hair …

11 Role of Anthocyanins in Skin Aging and UV-Induced Skin Damage

LE Rojo, DE Roopchand, B Graf… - … in health and …, 2013 - books.google.com
The visible changes associated with chronological aging and chronic sun exposure,
especially to the face, head, and neck areas, are particularly concerning for a significant …

α6 Integrin (α6high)/Transferrin Receptor (CD71)low Keratinocyte Stem Cells Are More Potent for Generating Reconstructed Skin Epidermis Than Rapid Adherent …

E Metral, N Bechetoille, F Demarne, W Rachidi… - International journal of …, 2017 - mdpi.com
The epidermis basal layer is composed of two keratinocyte populations: Keratinocyte Stem
cells (KSC) and Transitory Amplifying (TA) cells that arise from KSC division. Unfortunately …

The Antiaging Properties of Andrographis paniculata by Activation Epidermal Cell Stemness

J You, KB Roh, Z Li, G Liu, J Tang, S Shin, D Park… - Molecules, 2015 - mdpi.com
Andrographis paniculata (A. paniculata, Chuanxinlian), a medicinal herb with an extremely
bitter taste that is native to China and other parts of Southeast Asia, possesses immense …

[HTML][HTML] Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight

L Dal Pozzo, Z Xu, S Lin, J Wang, Y Wang… - Biomedicine & …, 2024 - Elsevier
Multiple epigenetic factors play a regulatory role in maintaining the homeostasis of
cutaneous components and are implicated in the aging process of the skin. They have been …

The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging

E Raja, G Changarathil, L Oinam, J Tsunezumi… - EMBO …, 2022 - embopress.org
Tissue stem cells (SCs) divide infrequently as a protective mechanism against internal and
external stresses associated with aging. Here, we demonstrate that slow‐and fast‐cycling …