The tauopathies encompass over 20 adult neurodegenerative diseases and are
characterized by the dysfunction and accumulation of insoluble tau protein. Among them …

Tau protein is associated with many neurodegenerative disorders known as tauopathies.
Aggregates of tau are thought of as a main contributor to neurodegeneration in these …

The aggregation of misfolded tau into neurotoxic fibrils is linked to the progression of
Alzheimer's disease (AD) and related tauopathies. Disease-associated conformations of …

Distinctive post-translational modifications (PTM) characterize tau inclusions found in
tauopathy patients. Using detergent-insoluble tau isolated from Alzheimer's disease (AD …

This study investigates various pathological tau isoforms in the retina of individuals with
early and advanced Alzheimer's disease (AD), exploring their connection with disease …

Abnormal accumulation of misfolded and hyperphosphorylated tau protein in brain is the
defining feature of several neurodegenerative diseases called tauopathies, including …

Antibodies are essential research tools whose performance directly impacts research
conclusions and reproducibility. Owing to its central role in Alzheimer's disease and other …

Diverse proteomics-based strategies have been applied to saliva to quantitatively identify
diagnostic and prognostic targets for oral cancer. Considering that these targets may be …

Abstract Alzheimer's disease (AD), the leading cause of dementia, is characterized by the
accumulation of amyloid plaques and neurofibrillary tangles in the brain. This condition …

Repetitive mild traumatic brain injury (rmTBI, eg, sports concussions) may be associated
with both acute and chronic symptoms and neurological changes. Despite the common …