Systemic lupus erythematosus (SLE) is a complex autoimmune disorder of unknown
etiology. Multifactorial interaction among various susceptible factors such as environmental …

Systemic sclerosis and systemic lupus erythematosus represent two distinct autoimmune
diseases belonging to the group of connective tissue disorders. Despite the great progress …

Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are two related
autoimmune diseases. In recent years, there has been sufficient evidence to suggest that …

Presence of autoantibodies targeting nuclear constituents, ie, double-stranded DNA and
small nuclear ribonucleoproteins (snRNPs), remain a cornerstone in systemic lupus …

Simple Summary Proline isomerization influences protein folding and function tremendously
and serves as a unique type of post-translational modification that regulates multiple …

Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease affecting multiple
organs characterized by a complex interplay of immune cells, factors and pathways resulting …

Central nervous system (CNS) involvement of systemic lupus erythematosus (SLE), termed
neuropsychiatric SLE (NPSLE), is a major and debilitating manifestation of the disease …

In the era of precision medicine, antibody-drug conjugates (ADCs) have emerged as a
cutting-edge therapeutic strategy. These innovative compounds combine the precision of …

Cancer collectively represents a major, debilitating source of global disease burden. While
we are just beginning to unravel the mysteries behind the multifarious pathways and …

The Helios protein (encoded by the IKZF2 gene) is a member of the Ikaros transcription
family and it has recently been proposed as a promising biomarker for systemic lupus …